Decreased proportion of switched memory B cells
Basic details
Preferred term: Decreased proportion of switched memory B cells
Alt. terms: smB- | Decreased proportion of class-switched memory B cells
HPO term: Decreased proportion of class-switched memory B cells
HPO code: HP:0030388
GenIA ID: 101
Last updated on: 2024-04-25 14:48:58
Cross ref. with other ontologies
NCIT: -
MESH: -
EFO: -
OAE: -
SNOMEDCT: -
ICD10: -
Description
A reduction in the normal proportion of class-switched memory (sm) B-cells (CD19+/CD27+/IgM-/IgD-) relative to the total number of B cells. EUROclass: smB- --> Number of sm B-cells is <2% of all B-cells. FreiburgClass: I --> Number of sm B-cells is <0.4% of all lymphocytes.
Hierarchical classification
PARENT terms
TERM
Decreased proportion of switched memory B cells
CHILD terms
Reported patients added to GenIA DB
SubjectID | Sex | Fam.ID | Age* | Population | MatchedTerm | Diagnosis | Reference & Pub.codes |
---|---|---|---|---|---|---|---|
101020 | F | 210008![]() |
- | German | Decreased proportion of switched memory B cells | NFKB1 insufficiency | PMID:34975878 [Fam.F005:P005]; PMID:32278790 [Fam.AU:II.3(II.3)]; PMID:29403474 [Patient 28 (11)]; PMID:150198 [Fam.AM:II.4(157)]; PMID:27461466 [Fam.199_01:28] |
101045 | M | 210205![]() |
23 | Caucasian | Decreased proportion of switched memory B cells | CTLA4 haploinsufficiency with autoimmune infiltration | PMID:25329329 [Fam.A:III.13(A.III.3)]; PMID:29729943 [Fam.A:III.3(9)]; PMID:34975878 [Fam.F018:III.2(P018)]; PMID:27418640 [P11(5)] |
101083 | M | 210479 | 38 | German | Decreased proportion of switched memory B cells | PMID:34975878 [Fam.F049:P049] | |
101090 | M | 211257 | - | Decreased proportion of switched memory B cells | CTLA4 haploinsufficiency with autoimmune infiltration | PMID:34975878 [Fam.F056:P056]; PMID:37740092 [P13] | |
101091 | M | 210911 | 22 | Decreased proportion of switched memory B cells | DiGeorge syndrome | PMID:34975878 [Fam.F057:P057]; PMID:35486341 [P180] | |
101171 | M | 210012![]() |
7 | Dutch | Decreased proportion of switched memory B cells | Immunodeficiency, common variable, 20 | PMID:25926555 [Patient(II.1)] |
101399 | F | 210189![]() |
- | German | Decreased proportion of switched memory B cells | Adenosine deaminase 2 deficiency | PMID:28493328 [P6]; PMID:26922074 [Fam.Index:II.1(sister1)] |
101403 | M | 210189![]() |
- | German | Decreased proportion of switched memory B cells | Adenosine deaminase 2 deficiency | PMID:28493328 [P3]; PMID:26922074 [Index(II.2)] |
101410 | F | 210902 | - | German | Decreased proportion of switched memory B cells | Adenosine deaminase 2 deficiency | PMID:34975878 [Fam.F141:P141]; PMID:28493328 [P4] |
101425 | M | 210205![]() |
47 | Caucasian | Decreased proportion of switched memory B cells | CTLA4 haploinsufficiency with autoimmune infiltration | PMID:25329329 [Fam.A:II.8(A.II.5)]; PMID:29729943 [Fam.A:II.8(A.II.5 (4))]; PMID:27418640 [P7(5)] |
101426 | M | 212173 | 3 | Iranian | Decreased proportion of switched memory B cells | Immunodeficiency, common variable, 8 | PMID:29528757 [Case 2]; PMID:26707784 [Fam.E:IV.2(P28)]; PMID:26993986 [Fam.F17:II.1(1)]; PMID:28512785 [P7] |
101461 | M | 210929 | - | German | Decreased proportion of switched memory B cells | NFKB1 insufficiency | PMID:34975878 [Fam.F153:P153]; PMID:32278790 [Z.I.1]; PMID:29403474 [Patient 27 (11)]; PMID:27923702 [Patient 6]; PMID:150198 [Fam.AL:151]; PMID:27461466 [Fam.830_01:27] |
101503 | M | 210237 | - | Abnormal B cell count | PMID:34975878 [Fam.F168:P168] | ||
101509 | F | 212459 | - | British | Decreased proportion of switched memory B cells | Activated p110-delta syndrome 1 | PMID:24136356 [Fam.A:III.2(P1)] |
101511 | M | 212459 | - | British | Decreased proportion of switched memory B cells | Activated p110-delta syndrome 1 | PMID:24136356 [Fam.A:III.3(P2)] |
101512 | M | 212459 | - | British | Decreased proportion of switched memory B cells | Activated p110-delta syndrome 1 | PMID:24136356 [Fam.A:III.4(P3)] |
101541 | M | 212461 | - | Slovenian | Decreased proportion of switched memory B cells | Activated p110-delta syndrome 1 | PMID:24136356 [Fam.C:II.1(P8)] |
101543 | F | 210011 | 23 | Decreased proportion of switched memory B cells | PMID:34975878 [Fam.F179:P179] | ||
101548 | M | 212462 | - | Irish | Decreased proportion of switched memory B cells | Activated p110-delta syndrome 1 | PMID:24136356 [Fam.D:III.1(P9)] |
101549 | F | 212463 | - | British | Decreased proportion of switched memory B cells | Activated p110-delta syndrome 1 | PMID:24136356 [Fam.E:I.1(P13)] |
101551 | M | 212463 | - | British | Decreased proportion of switched memory B cells | Activated p110-delta syndrome 1 | PMID:24136356 [Fam.E:II.1(P12)] |
101561 | F | 212465 | - | French | Decreased proportion of switched memory B cells | Activated p110-delta syndrome 1 | PMID:24136356 [Fam.G:II.3(P16)] |
101575 | M | 210900 | - | German | Decreased proportion of switched memory B cells | Adenosine deaminase 2 deficiency | PMID:34975878 [Fam.F198:P198]; PMID:28493328 [P2] |
101579 | F | 210773 | - | Turkish | Decreased proportion of switched memory B cells | Adenosine deaminase 2 deficiency | PMID:28493328 [P1]; PMID:31857261 [Patient 13] |
101617 | M | 210994 | - | Decreased proportion of switched memory B cells | Immunodeficiency, common variable, 2 | PMID:34975878 [Fam.F212:P212] | |
101624 | M | 210946 | - | Abnormal B cell count | Agammaglobulinemia, X-linked 1 | PMID:34975878 [Fam.F215:P215] | |
101774 | M | 210908![]() |
- | Argentinian | Decreased proportion of switched memory B cells | Adenosine deaminase 2 deficiency | PMID:28493328 [P9(II.1)] |
101788 | M | 210950![]() |
- | Swiss | Decreased proportion of switched memory B cells | Adenosine deaminase 2 deficiency | PMID:28493328 [P7(II.1)] |
101789 | M | 210950![]() |
- | Swiss | Decreased proportion of switched memory B cells | Adenosine deaminase 2 deficiency | PMID:28493328 [Fam.P7:II.2(P8)] |
101794 | F | 211030 | - | Italian | Decreased proportion of switched memory B cells | Adenosine deaminase 2 deficiency | PMID:28493328 [P5] |
101798 | M | 211117 | 45 | Decreased proportion of switched memory B cells | Adenosine deaminase 2 deficiency | PMID:28493328 [P11] | |
101802 | F | 211221![]() |
38 | German | Decreased proportion of switched memory B cells | NFKB1 insufficiency | PMID:33995346 [Fam.A:III.2(Pat2)]; PMID:150198 [Fam.DV:III.2(528)]; PMID:36105815 [Fam.Y350C:III.2(Y350C/2)] |
101803 | F | 211221![]() |
- | German | Decreased proportion of switched memory B cells | NFKB1 insufficiency | PMID:33995346 [Fam.A:II.2(Pat1)]; PMID:150198 [Fam.DV:II.2(521)]; PMID:36105815 [Fam.Y350C:II.2(Y350C/1)] |
101813 | F | 211525 | 52,52 | Abnormal B cell count,Decreased proportion of switched memory B cells | PMID:34975878 [Fam.F273:P273] | ||
101827 | M | 211564 | 28 | Decreased proportion of switched memory B cells | PMID:34975878 [Fam.F291:P291] | ||
101925 | M | 210095 | - | Indian | Decreased proportion of memory B cells | Hyper-IgE recurrent infection syndrome 1 | PMID:34390440 [CMC20]; PMID:28667753 [case] |
102138 | M | 214393![]() |
62 | North American | Decreased proportion of switched memory B cells | Immunodeficiency, common variable, 14 | PMID:27016798 [Fam.Patient:II.2(F)]; PMID:37876937 [Fam.A:II.1(A.3)] |
102141 | F | 214393![]() |
18 | North American | Decreased proportion of switched memory B cells | Immunodeficiency, common variable, 14 | PMID:27016798 [Patient(III.1)]; PMID:37876937 [Fam.A:III.1(A.1)] |
102142 | M | 214393![]() |
22 | North American | Decreased proportion of switched memory B cells | Immunodeficiency, common variable, 14 | PMID:27016798 [Fam.Patient:III.2(B)]; PMID:37876937 [Fam.A:III.2(A.2)] |
102168 | M | 214767![]() |
3 | Georgian | Decreased proportion of switched memory B cells | Agammaglobulinemia 14 | PMID:33571536 [P-FR1(II.3)] |
102410 | F | 214947![]() |
5 | South Asian | Decreased proportion of switched memory B cells | Hyper-IgE recurrent infection syndrome 4B | PMID:28747427 [Fam.A:II.3(P1)] |
102466 | M | 214962![]() |
5 | Polish | Decreased proportion of switched memory B cells | Immunodeficiency 94 | PMID:33517393 [Patient(III.7)] |
102731 | F | 214982![]() |
8,- | Colombian | Decreased proportion of memory B cells,Decreased proportion of switched memory B cells | Immunodeficiency 99 | PMID:32484799 [Patient(II.2)] |
102865 | F | 214996![]() |
7,- | Italian | Decreased proportion of memory B cells,Decreased proportion of switched memory B cells | ARPC1B deficiency | Hartnup disease | PMID:35967303 [PtII-1(II.1)]; PMID:35967303 [PtII-1(II.1)] |
102984 | F | 215074![]() |
- | European/American | Decreased proportion of memory B cells | Immunodeficiency 97 | PMID:31554793 [A.1(II.1)] |
103062 | M | 215096![]() |
7 | Finnish | Decreased proportion of switched memory B cells | Seizures, cortical blindness, microcephaly syndrome | PMID:33662367 [Fam.F2:II.2(P3)] |
103067 | F | 215097![]() |
3 | Finnish | Decreased proportion of switched memory B cells | Seizures, cortical blindness, microcephaly syndrome | PMID:33662367 [Fam.F3:II.3(P4)] |
103072 | F | 215098![]() |
25 | Finnish | Decreased proportion of switched memory B cells | Seizures, cortical blindness, microcephaly syndrome | PMID:33662367 [Fam.F4:II.1(P5)] |
103110 | M | 215099![]() |
3 | Omani | Decreased proportion of switched memory B cells | Seizures, cortical blindness, microcephaly syndrome | PMID:33662367 [Fam.F5:V.2(P7)] |
103293 | M | 215115 | 44 | Decreased proportion of switched memory B cells | Immunodeficiency 82 with systemic inflammation | PMID:33782605 [P6] | |
103830 | F | 215256![]() |
- | European | Decreased proportion of memory B cells | Adenosine deaminase 2 deficiency | PMID:24552284 [Fam.1:II.2(P1)] |
103834 | F | 215257![]() |
- | European | Decreased proportion of memory B cells | Adenosine deaminase 2 deficiency | PMID:24552284 [Fam.2:II.3(P2)] |
103839 | M | 215258![]() |
- | European | Decreased proportion of memory B cells | Adenosine deaminase 2 deficiency | PMID:24552284 [Fam.3:II.3(P3)] |
103848 | M | 215260![]() |
- | European | Decreased proportion of memory B cells | Adenosine deaminase 2 deficiency | PMID:24552284 [Fam.5:II.1(P5)] |
104410 | M | 215525![]() |
1 | Japanese | Decreased proportion of switched memory B cells | Early-onset atopic inflammation | PMID:36538978 [Patient(II.2)] |
104414 | M | 215526![]() |
8 | Turkish | Decreased proportion of memory B cells | Early-onset atopic inflammation | PMID:36758835 [Patient(V.3)] |
104534 | M | 215546![]() |
- | Caucasian | Decreased proportion of switched memory B cells | X-linked multisystem autoinflammatory disease with immune dysregulation | PMID:36952639 [Fam.C:II.1(Patient C)] |
104541 | M | 215550![]() |
- | North African | Decreased proportion of switched memory B cells | X-linked multisystem autoinflammatory disease with immune dysregulation | PMID:36952639 [Fam.G:II.1(Patient G)] |
104842 | M | 215579![]() |
50 | European | Decreased proportion of switched memory B cells | NFKB1 insufficiency | PMID:32278790 [Fam.NZ:II.1(II.1)]; PMID:26279205 [Fam.NZ:II.1(II1)]; PMID:29403474 [Fam.NZ (5):II.1(II1)]; PMID:29806948 [Fam.NZ:II.1(II.1)]; PMID:30323807 [Fam.2:II.1(II.1)]; PMID:150198 [Fam.AC:II.1(108)] |
104844 | F | 215579![]() |
76 | European | Decreased proportion of switched memory B cells | NFKB1 insufficiency | PMID:32278790 [Fam.NZ:I.2(I.2)]; PMID:26279205 [Fam.NZ:I.2(I2)]; PMID:29403474 [Fam.NZ (5):I.2(I2)]; PMID:29806948 [Fam.NZ:I.2(I.2)]; PMID:30323807 [Fam.2:I.2(I.2)]; PMID:150198 [Fam.AC:I.2(107)] |
104875 | M | 215579![]() |
46 | European | Decreased proportion of switched memory B cells | NFKB1 insufficiency | PMID:32278790 [Fam.NZ:II.3(II.3)]; PMID:26279205 [Fam.NZ:II.3(II3)]; PMID:29806948 [Fam.NZ:II.3(II.3)]; PMID:30323807 [Fam.2:II.3(II.3)]; PMID:150198 [Fam.AC:II.3(110)] |
104876 | F | 215579![]() |
15 | European | Decreased proportion of switched memory B cells | NFKB1 insufficiency | PMID:32278790 [Fam.NZ:III.1(III.1)]; PMID:26279205 [Fam.NZ:III.1(III1)]; PMID:29806948 [Fam.NZ:III.1(III.1)]; PMID:30323807 [Fam.2:III.1(III.1)]; PMID:150198 [Fam.AC:III.1(112)] |
104923 | M | 215620![]() |
- | Decreased proportion of switched memory B cells | Immunodeficiency, common variable, 14 | PMID:36193988 [Patient(II.1)]; PMID:37876937 [Fam.D:II.1(D.1)] | |
104972 | F | 215622![]() |
55 | Dutch | Decreased proportion of switched memory B cells | NFKB1 insufficiency | PMID:32278790 [Fam.NA:III.14(III.14)]; PMID:26279205 [Fam.NL1:III.14(36)]; PMID:29403474 [Fam.NL1 (5):III.14(36)]; PMID:11583829 [Fam.1:III.14(III:14)]; PMID:16639407 [Fam.1:III.14(36)]; PMID:27923702 [Patient 4]; PMID:27555455 [Patient 2]; PMID:150198 [Fam.AA:III.14(040)] |
105019 | M | 215624![]() |
- | French | Decreased proportion of memory B cells | Hyper-IgE recurrent infection syndrome 1 | PMID:31346092 [P1(III.4)] |
105065 | M | 215624![]() |
- | French | Decreased proportion of memory B cells | Hyper-IgE recurrent infection syndrome 1 | PMID:31346092 [Fam.P1:III.5(P7)] |
105066 | F | 215624![]() |
- | French | Decreased proportion of memory B cells | Hyper-IgE recurrent infection syndrome 1 | PMID:31346092 [Fam.P1:III.6(P3)] |
105131 | M | 215648 | 40 | Italian | Decreased proportion of switched memory B cells | NFKB1 insufficiency | PMID:32278790 [BG.I.1]; PMID:29403474 [Patient 1 (6)]; PMID:27923702 [Patient 1]; PMID:27555455 [Patient 1]; PMID:150198 [Fam.AN:160] |
105152 | F | 215655![]() |
- | Spanish | Decreased proportion of switched memory B cells | NFKB1 insufficiency | PMID:32278790 [V.I.1]; PMID:29403474 [Patient 26 (11)]; PMID:150198 [Fam.AK:I.2(149)]; PMID:27461466 [Fam.827_01:26] |
105197 | M | 215666![]() |
37 | Finnish | Decreased proportion of switched memory B cells | NFKB1 insufficiency | PMID:32278790 [Fam.F1:III.3(III.3)]; PMID:29403474 [Fam.1 (9):III.3(F1.III-3)]; PMID:28115215 [Fam.1:III.3(F1.III-3)]; PMID:150198 [Fam.AQ:III.3(177)]; PMID:36356849 [Fam.6:III.3(F6:III:3)]; PMID:36105815 [Fam.H67R:III.3(H67R/4)] |
105212 | F | 215666![]() |
55 | Finnish | Decreased proportion of switched memory B cells | NFKB1 insufficiency | PMID:32278790 [Fam.F1:II.4(II.4)]; PMID:29403474 [Fam.1 (9):II.4(F1.II-4)]; PMID:28115215 [Fam.1:II.4(F1.II-4)]; PMID:150198 [Fam.AQ:II.4(174)]; PMID:36356849 [Fam.6:II.4(F6:II:4)]; PMID:36105815 [Fam.H67R:II.4(H67R/2)] |
105214 | F | 215666![]() |
40 | Finnish | Decreased proportion of switched memory B cells | NFKB1 insufficiency | PMID:32278790 [Fam.F1:III.2(III.2)]; PMID:29403474 [Fam.1 (9):III.2(F1.III-2)]; PMID:28115215 [Fam.1:III.2(F1.III-2)]; PMID:150198 [Fam.AQ:III.2(176)]; PMID:36356849 [Fam.6:III.2(F6:III:2)]; PMID:36105815 [Fam.H67R:III.2(H67R/3)] |
105221 | M | 215666![]() |
10 | Finnish | Decreased proportion of switched memory B cells | NFKB1 insufficiency | PMID:32278790 [Fam.F1:IV.2(IV.2)]; PMID:28115215 [Fam.1:IV.1(F1.IV-1)]; PMID:150198 [Fam.AQ:IV.1(183)]; PMID:36356849 [Fam.6:IV.1(F6:IV:1)]; PMID:36105815 [Fam.H67R:IV.1(H67R/8)] |
105222 | F | 215666![]() |
7 | Finnish | Decreased proportion of switched memory B cells | NFKB1 insufficiency | PMID:32278790 [Fam.F1:IV.1(IV.1)]; PMID:29403474 [Fam.1 (9):IV.2(F1.IV-2)]; PMID:28115215 [Fam.1:IV.2(F1.IV-2)]; PMID:150198 [Fam.AQ:IV.2(184)]; PMID:36356849 [Fam.6:IV.2(F6:IV:2)]; PMID:36105815 [Fam.H67R:IV.2(H67R/9)] |
105225 | F | 215671![]() |
61 | Finnish | Decreased proportion of switched memory B cells | NFKB1 insufficiency | PMID:32278790 [Fam.F2:II.2(II.2)]; PMID:29403474 [Fam.2 (9):II.3(F2.II-3)]; PMID:28115215 [Fam.2:II.3(F2.II-3)]; PMID:150198 [Fam.AR:II.3(191)]; PMID:36356849 [Fam.5:II.2(F5:II:2)] |
105231 | M | 215671![]() |
32 | Finnish | Decreased proportion of switched memory B cells | NFKB1 insufficiency | PMID:32278790 [Fam.F2:III.2(III.2)]; PMID:29403474 [Fam.2 (9):III.2(F2.III-2)]; PMID:28115215 [Fam.2:III.2(F2.III-2)]; PMID:150198 [Fam.AR:III.2(193)]; PMID:36356849 [Fam.5:III.2(F5:III:2)] |
105232 | M | 215672![]() |
62 | Finnish | Decreased proportion of switched memory B cells | NFKB1 insufficiency | PMID:32278790 [Fam.F3:II.1(II.1)]; PMID:29403474 [Fam.3 (9):II.1(F3.II-1)]; PMID:28115215 [Fam.3:II.1(F3.II-1)]; PMID:150198 [Fam.AS:II.1(196)]; PMID:36356849 [Fam.3:II.1(F3:II:1)]; PMID:36892687 [II:1(II.1)]; PMID:38593810 [Fam.1:II.1(F1.II-1)] |
105238 | M | 215672![]() |
56 | Finnish | Decreased proportion of switched memory B cells | NFKB1 insufficiency | PMID:32278790 [Fam.F3:II.5(II.5)]; PMID:29403474 [Fam.3 (9):II.5(F3.II-5)]; PMID:28115215 [Fam.3:II.5(F3.II-5)]; PMID:150198 [Fam.AS:II.9(204)]; PMID:36356849 [Fam.3:II.9(F3:II:9)]; PMID:36892687 [II:5(II.5)]; PMID:38593810 [Fam.1:II.9(F1.II-5)] |
105245 | M | 215674![]() |
- | Caucasian | Decreased proportion of switched memory B cells | NFKB1 insufficiency | PMID:32278790 [Fam.AN:II.2(II.1)]; PMID:29403474 [Fam.(12):I.1(P9.1)]; PMID:28983403 [Fam.1:I.1(P9.1)]; PMID:150198 [Fam.AT:II.1(223)] |
105246 | M | 215674![]() |
- | Caucasian | Decreased proportion of switched memory B cells | NFKB1 insufficiency | PMID:32278790 [Fam.AN:III.2(III.1)]; PMID:29403474 [Fam.(12):II.1(P9.2)]; PMID:28983403 [Fam.1:II.1(P9.2)]; PMID:150198 [Fam.AT:III.2(226)] |
105279 | F | 215685![]() |
- | European | Decreased proportion of switched memory B cells | NFKB1 insufficiency | PMID:32278790 [Fam.B:II.1(II.1)]; PMID:29477724 [Fam.B:II.1(II:1)]; PMID:150198 [Fam.AV:II.1(244)] |
105284 | F | 215640![]() |
- | European | Decreased proportion of switched memory B cells | NFKB1 insufficiency | PMID:32278790 [Fam.A:II.1(II.1)]; PMID:29477724 [Fam.A:II.1(II:1)]; PMID:150198 [Fam.AU:II.2(230)] |
105287 | F | 215640![]() |
- | European | Decreased proportion of switched memory B cells | NFKB1 insufficiency | PMID:32278790 [Fam.A:II.4(II.4)]; PMID:29477724 [Fam.A:II.4(II:4)]; PMID:150198 [Fam.AU:II.5(233)] |
105290 | M | 215640![]() |
- | European | Decreased proportion of switched memory B cells | NFKB1 insufficiency | PMID:32278790 [Fam.A:III.2(III.2)]; PMID:29477724 [Fam.A:III.2(III:2)]; PMID:150198 [Fam.AU:III.2(235)]; PMID:32918165 [Fam.A:III.2(brother)] |
105296 | F | 215686![]() |
- | European | Decreased proportion of switched memory B cells | NFKB1 insufficiency | PMID:32278790 [Fam.C:I.2(I.2)]; PMID:29477724 [Fam.C:I.2(I:2)]; PMID:150198 [Fam.AW:I.2(246)] |
105304 | F | 215686![]() |
- | European | Decreased proportion of switched memory B cells | NFKB1 insufficiency | PMID:32278790 [Fam.C:III.1(III.1)]; PMID:29477724 [Fam.C:III.1(III:1)]; PMID:150198 [Fam.AW:III.1(253)] |
105306 | M | 215686![]() |
- | European | Decreased proportion of switched memory B cells | NFKB1 insufficiency | PMID:32278790 [Fam.C:III.3(III.3)]; PMID:29477724 [Fam.C:III.3(III:3)]; PMID:150198 [Fam.AW:III.3(255)] |
105307 | M | 215686![]() |
- | European | Decreased proportion of switched memory B cells | NFKB1 insufficiency | PMID:32278790 [Fam.C:III.4(III.4)]; PMID:29477724 [Fam.C:III.4(III:4)]; PMID:150198 [Fam.AW:III.4(256)] |
105308 | F | 215687![]() |
- | European | Decreased proportion of switched memory B cells | NFKB1 insufficiency | PMID:32278790 [Fam.D:II.2(II.2)]; PMID:29477724 [Fam.D:II.2(II:2)]; PMID:150198 [Fam.AX:II.2(260)] |
105311 | F | 215687![]() |
- | European | Decreased proportion of switched memory B cells | NFKB1 insufficiency | PMID:32278790 [Fam.D:I.2(I.2)]; PMID:29477724 [Fam.D:I.2(I:2)]; PMID:150198 [Fam.AX:I.2(258)] |
105313 | M | 215688![]() |
- | European | Decreased proportion of switched memory B cells | NFKB1 insufficiency | PMID:32278790 [E.II.1]; PMID:29477724 [Fam.E:II.1(II:1)]; PMID:150198 [Fam.AY:II.2(264)]; PMID:36105815 [Fam.I281M:II.2(I281M/1)] |
105317 | M | 215692![]() |
- | European | Decreased proportion of switched memory B cells | NFKB1 insufficiency | PMID:32278790 [Fam.J:III.2(III.2)]; PMID:29477724 [Fam.J:III.2(III:2)]; PMID:150198 [Fam.BD:III.2(277)] |
105337 | U | 215699 | - | European | Decreased proportion of switched memory B cells | NFKB1 insufficiency | PMID:32278790 [I.II.1]; PMID:29477724 [Fam.I:II.1(I:II-1)]; PMID:150198 [Fam.BC:268] |
105363 | F | 215722 | 13 | Afro-American | Decreased proportion of switched memory B cells | CTLA4 haploinsufficiency with autoimmune infiltration | PMID:29729943 [Fam.X:II.1(X.II.1 (59))]; PMID:28366794 [Fam.A:II.1(P1)] |
105423 | M | 215765![]() |
3 | Caucasian | Decreased proportion of switched memory B cells | NFKB1 insufficiency | PMID:150198 [Fam.BO:II.2(308)]; PMID:30761159 [Fam.1:II.2(patient)] |
105428 | M | 215766![]() |
3 | Admixed | Decreased proportion of switched memory B cells | Adenosine deaminase 2 deficiency | PMID:26867732 [Fam.F:II.2(P9)]; PMID:25457153 [Fam.1:II.3(P2)]; PMID:25075846 [Fam.1:II.3(younger-sib)] |
105432 | M | 215767![]() |
33 | Caucasian | Decreased proportion of switched memory B cells | NFKB1 insufficiency | PMID:150198 [Fam.BR:II.1(316)]; PMID:31803180 [Fam.A:II.1(S1)]; PMID:34619682 [P.200] |
105465 | M | 215772![]() |
32 | Russian | Decreased proportion of switched memory B cells | NFKB1 insufficiency | PMID:150198 [Fam.BS:II.1(319)]; PMID:31803180 [Fam.B:II.1(S3)] |
105466 | M | 215772![]() |
23 | Russian | Decreased proportion of switched memory B cells | NFKB1 insufficiency | PMID:150198 [Fam.BS:II.2(320)]; PMID:31803180 [Fam.B:II.2(S4)] |
105475 | F | 215776![]() |
- | European | Decreased proportion of switched memory B cells | Ezrin immunodeficiency | PMID:37301410 [P1(II.4)] |
105481 | M | 215777![]() |
- | Haitian/Hispanic | Decreased proportion of switched memory B cells | Activated p110-delta syndrome 1 | PMID:24165795 [Fam.A:II.1(A.1)] |
105484 | F | 215778![]() |
- | Caucasian | Decreased proportion of switched memory B cells | Activated p110-delta syndrome 1 | PMID:24165795 [Fam.B:III.1(B.III.1)] |
105487 | F | 215780![]() |
- | Afro-American | Decreased proportion of switched memory B cells | Activated p110-delta syndrome 1 | PMID:24165795 [Fam.G:II.1(G.1)] |
105504 | F | 215783![]() |
- | Asian | Decreased proportion of switched memory B cells | Activated p110-delta syndrome 1 | PMID:24165795 [Fam.E:II.1(E.1)] |
105509 | M | 215784![]() |
- | Caucasian | Decreased proportion of switched memory B cells | Activated p110-delta syndrome 1 | PMID:24165795 [Fam.D:II.1(D.II.1)] |
105513 | F | 215787![]() |
- | Caucasian | Decreased proportion of switched memory B cells | Activated p110-delta syndrome 1 | PMID:24165795 [Fam.F:II.1(F.II.1)] |
105549 | F | 215801 | 12 | Caucasian | Decreased proportion of memory B cells | CTLA4 haploinsufficiency with autoimmune infiltration | PMID:29200144 [Fam.A:IV.1(P1)] |
105571 | U | 215810 | 5 | Decreased proportion of memory B cells | Activated p110-delta syndrome 1 | PMID:24698326 [P3] | |
105575 | U | 215814 | 11 | Decreased proportion of switched memory B cells | Activated p110-delta syndrome 1 | PMID:24698326 [P6] | |
105623 | M | 215822 | 13 | Caucasian | Decreased proportion of memory B cells | Activated p110-delta syndrome 1 | PMID:25352054 [Fam.1:II.6(P2)] |
105626 | M | 215822 | - | Caucasian | Decreased proportion of switched memory B cells | Activated p110-delta syndrome 1 | PMID:25352054 [Fam.1:III.1(P3)] |
105627 | F | 215822 | 3 | Caucasian | Decreased proportion of switched memory B cells | Activated p110-delta syndrome 1 | PMID:25352054 [Fam.1:III.2(P4)] |
105628 | F | 215822 | 3 | Caucasian | Decreased proportion of memory B cells | Activated p110-delta syndrome 1 | PMID:25352054 [Fam.1:III.3(P5)] |
105635 | F | 215829 | - | Caucasian | Decreased proportion of memory B cells | Activated p110-delta syndrome 1 | PMID:26371693 [1] |
105659 | F | 215836 | - | Decreased proportion of switched memory B cells | Activated p110-delta syndrome 1 | PMID:26437962 [Fam.A:II.2(Sibling 2)] | |
105660 | F | 215836 | - | Decreased proportion of switched memory B cells | Activated p110-delta syndrome 1 | PMID:26437962 [Fam.A:II.3(Sibling 3)] | |
105757 | F | 215860 | - | North American | Decreased proportion of switched memory B cells | NFKB1 insufficiency | PMID:32278790 [BJ.I.1]; PMID:150198 [Fam.CX:443] |
105778 | F | 215871![]() |
8 | Spanish | Decreased proportion of switched memory B cells | NFKB1 insufficiency | PMID:32278790 [CB.I.1]; PMID:150198 [Fam.DM:II.1(472)]; PMID:36105815 [Fam.G386R:II.1(G386R/1)] |
105791 | F | 215877![]() |
- | Spanish | Decreased proportion of switched memory B cells | Immunodeficiency, common variable, 14 | PMID:37876937 [Fam.1:II.1(1.1)] |
105793 | M | 215877![]() |
- | Spanish | Decreased proportion of switched memory B cells | Immunodeficiency, common variable, 14 | PMID:37876937 [Fam.1:I.2(1.2)] |
105839 | M | 215888![]() |
- | Romani | Decreased proportion of switched memory B cells | Immunodeficiency, common variable, 14 | PMID:37876937 [Fam.3:II.1(3.1)] |
105943 | M | 215912![]() |
20 | Colombian/Swiss | Decreased proportion of memory B cells | Hyper-IgE recurrent infection syndrome 4A | PMID:37273120 [Fam.C:II.1(P8)] |
106304 | M | 215981![]() |
54 | Chinese (China) | Decreased proportion of switched memory B cells | NFKB1 insufficiency | PMID:150198 [Fam.FO:II.5(717)]; PMID:36571238 [Fam.1:II.5(II:5[P1])] |
106312 | M | 215981![]() |
29 | Chinese (China) | Decreased proportion of switched memory B cells | NFKB1 insufficiency | PMID:150198 [Fam.FO:III.1(719)]; PMID:36571238 [Fam.1:III.1(III:1[P2])] |
106393 | F | 216006![]() |
- | German | Decreased proportion of switched memory B cells | CTLA4 haploinsufficiency with autoimmune infiltration | PMID:36273440 [III.3(III.3)] |
106409 | M | 216010![]() |
42 | Chinese (China) | Decreased proportion of switched memory B cells | NFKB1 insufficiency | PMID:150198 [Fam.FT:II.2(741)]; PMID:37775675 [Fam.1:II.2(patient)] |
106463 | F | 216023![]() |
- | Japanese | Decreased proportion of switched memory B cells | NFKB1 insufficiency | PMID:150198 [Fam.FX:II.3(779)]; PMID:38514645 [Fam.1:II.3(proband)] |
106470 | F | 216023![]() |
3 | Japanese | Decreased proportion of switched memory B cells | NFKB1 insufficiency | PMID:150198 [Fam.FX:III.1(781)]; PMID:38514645 [Fam.1:III.1(III:1)] |
106592 | M | 216085 | 16,16 | Decreased proportion of memory B cells,Decreased proportion of switched memory B cells | CTLA4 haploinsufficiency with autoimmune infiltration | PMID:34116213 [Fam.A:II.1(P1)] | |
106610 | F | 216089![]() |
- | Australian | Decreased proportion of switched memory B cells | Agammaglobulinemia 8A | Immunodeficiency, common variable, 2 | PMID:30323807 [Fam.1:II.2(II.2)]; PMID:30323807 [Fam.1:II.2(II.2)]; PMID:29114388 [Fam.A:II.2(II.2)]; PMID:29114388 [Fam.A:II.2(II.2)] |
106615 | M | 216089![]() |
- | Australian | Decreased proportion of switched memory B cells | Immunodeficiency, common variable, 2 | PMID:30323807 [Fam.1:II.4(II.4)]; PMID:29114388 [Fam.A:II.4(II.4)] |
106616 | M | 216089![]() |
- | Australian | Decreased proportion of switched memory B cells | Agammaglobulinemia 8A | PMID:30323807 [Fam.1:III.1(III.1)]; PMID:29114388 [Fam.A:III.1(III.1)] |
106625 | F | 216092![]() |
- | Admixed | Decreased proportion of memory B cells | Autoinflammation, immune dysregulation, and eosinophilia | PMID:38563820 [Fam.5:II.2(P13)] |
106637 | M | 216096![]() |
- | Danish | Decreased proportion of switched memory B cells | Infantile-Onset Multisystem Autoimmune Disease 1 | PMID:32047491 [P3(II.1)] |
106646 | M | 216099 | 22 | Decreased proportion of switched memory B cells | CTLA4 haploinsufficiency with autoimmune infiltration | PMID:34628649 [Patient(III.1)] | |
106794 | F | 216145![]() |
27 | German | Decreased proportion of switched memory B cells | Immunodeficiency, common variable, 14 | PMID:34619682 [P.263]; PMID:39059757 [Fam.1:II.2(P2)] |
106807 | F | 216145![]() |
16 | German | Decreased proportion of switched memory B cells | Immunodeficiency, common variable, 14 | PMID:34619682 [P.159]; PMID:39059757 [Fam.1:II.1(P1)] |
106812 | F | 216158 | 31 | Decreased proportion of switched memory B cells | Immunodeficiency, common variable, 14 | PMID:39059757 [P4] | |
106819 | M | 216163![]() |
54 | Chinese (China) | Decreased proportion of switched memory B cells | Immunodeficiency, common variable, 1 | PMID:36571238 [Fam.2:II.2(II:2[P3])] |
106953 | M | 216195 | - | Decreased proportion of switched memory B cells | NFKB1 insufficiency | PMID:150198 [Fam.GA:793]; PMID:38901617 [Fam.1:I.1(P1)] | |
107156 | F | 216365![]() |
10 | Turkish | Decreased proportion of switched memory B cells | Hyper-IgE recurrent infection syndrome 2 | PMID:39437980 [Fam.B:II.2(Patient 2)] |
*Age: age reported at the first known time of manifestation; PMID: PubMed ID; GRID: GenIA reference ID (ref. not in PubMed).