Decreased proportion of switched memory B cells

Basic details

Preferred term: Decreased proportion of switched memory B cells
Alt. terms: smB- | Decreased proportion of class-switched memory B cells

HPO term: Decreased proportion of class-switched memory B cells
HPO code: HP:0030388

GenIA ID: 101
Last updated on: 2024-04-25 14:48:58

Cross ref. with other ontologies

NCIT: -
MESH: -
EFO: -
OAE: -
SNOMEDCT: -
ICD10: -

Description

A reduction in the normal proportion of class-switched memory (sm) B-cells (CD19+/CD27+/IgM-/IgD-) relative to the total number of B cells. EUROclass: smB- --> Number of sm B-cells is <2% of all B-cells. FreiburgClass: I --> Number of sm B-cells is <0.4% of all lymphocytes.

Hierarchical classification

TERM

Decreased proportion of switched memory B cells

CHILD terms

Reported patients added to GenIA DB

SubjectID Sex Fam.ID Age* Population MatchedTerm Diagnosis Reference & Pub.codes
101020 F 210008tree icon - German Decreased proportion of switched memory B cells NFKB1 insufficiency PMID:34975878 [Fam.F005:P005]; PMID:32278790 [Fam.AU:II.3(II.3)]; PMID:29403474 [Patient 28 (11)]; PMID:150198 [Fam.AM:II.4(157)]; PMID:27461466 [Fam.199_01:28]
101045 M 210205tree icon 23 Caucasian Decreased proportion of switched memory B cells CTLA4 haploinsufficiency with autoimmune infiltration PMID:25329329 [Fam.A:III.13(A.III.3)]; PMID:29729943 [Fam.A:III.3(9)]; PMID:34975878 [Fam.F018:III.2(P018)]; PMID:27418640 [P11(5)]
101083 M 210479 38 German Decreased proportion of switched memory B cells PMID:34975878 [Fam.F049:P049]
101090 M 211257 - Decreased proportion of switched memory B cells CTLA4 haploinsufficiency with autoimmune infiltration PMID:34975878 [Fam.F056:P056]; PMID:37740092 [P13]
101091 M 210911 22 Decreased proportion of switched memory B cells DiGeorge syndrome PMID:34975878 [Fam.F057:P057]; PMID:35486341 [P180]
101171 M 210012tree icon 7 Dutch Decreased proportion of switched memory B cells Immunodeficiency, common variable, 20 PMID:25926555 [Patient(II.1)]
101399 F 210189tree icon - German Decreased proportion of switched memory B cells Adenosine deaminase 2 deficiency PMID:28493328 [P6]; PMID:26922074 [Fam.Index:II.1(sister1)]
101403 M 210189tree icon - German Decreased proportion of switched memory B cells Adenosine deaminase 2 deficiency PMID:28493328 [P3]; PMID:26922074 [Index(II.2)]
101410 F 210902 - German Decreased proportion of switched memory B cells Adenosine deaminase 2 deficiency PMID:34975878 [Fam.F141:P141]; PMID:28493328 [P4]
101425 M 210205tree icon 47 Caucasian Decreased proportion of switched memory B cells CTLA4 haploinsufficiency with autoimmune infiltration PMID:25329329 [Fam.A:II.8(A.II.5)]; PMID:29729943 [Fam.A:II.8(A.II.5 (4))]; PMID:27418640 [P7(5)]
101426 M 212173 3 Iranian Decreased proportion of switched memory B cells Immunodeficiency, common variable, 8 PMID:29528757 [Case 2]; PMID:26707784 [Fam.E:IV.2(P28)]; PMID:26993986 [Fam.F17:II.1(1)]; PMID:28512785 [P7]
101461 M 210929 - German Decreased proportion of switched memory B cells NFKB1 insufficiency PMID:34975878 [Fam.F153:P153]; PMID:32278790 [Z.I.1]; PMID:29403474 [Patient 27 (11)]; PMID:27923702 [Patient 6]; PMID:150198 [Fam.AL:151]; PMID:27461466 [Fam.830_01:27]
101503 M 210237 - Abnormal B cell count PMID:34975878 [Fam.F168:P168]
101509 F 212459 - British Decreased proportion of switched memory B cells Activated p110-delta syndrome 1 PMID:24136356 [Fam.A:III.2(P1)]
101511 M 212459 - British Decreased proportion of switched memory B cells Activated p110-delta syndrome 1 PMID:24136356 [Fam.A:III.3(P2)]
101512 M 212459 - British Decreased proportion of switched memory B cells Activated p110-delta syndrome 1 PMID:24136356 [Fam.A:III.4(P3)]
101541 M 212461 - Slovenian Decreased proportion of switched memory B cells Activated p110-delta syndrome 1 PMID:24136356 [Fam.C:II.1(P8)]
101543 F 210011 23 Decreased proportion of switched memory B cells PMID:34975878 [Fam.F179:P179]
101548 M 212462 - Irish Decreased proportion of switched memory B cells Activated p110-delta syndrome 1 PMID:24136356 [Fam.D:III.1(P9)]
101549 F 212463 - British Decreased proportion of switched memory B cells Activated p110-delta syndrome 1 PMID:24136356 [Fam.E:I.1(P13)]
101551 M 212463 - British Decreased proportion of switched memory B cells Activated p110-delta syndrome 1 PMID:24136356 [Fam.E:II.1(P12)]
101561 F 212465 - French Decreased proportion of switched memory B cells Activated p110-delta syndrome 1 PMID:24136356 [Fam.G:II.3(P16)]
101575 M 210900 - German Decreased proportion of switched memory B cells Adenosine deaminase 2 deficiency PMID:34975878 [Fam.F198:P198]; PMID:28493328 [P2]
101579 F 210773 - Turkish Decreased proportion of switched memory B cells Adenosine deaminase 2 deficiency PMID:28493328 [P1]; PMID:31857261 [Patient 13]
101617 M 210994 - Decreased proportion of switched memory B cells Immunodeficiency, common variable, 2 PMID:34975878 [Fam.F212:P212]
101624 M 210946 - Abnormal B cell count Agammaglobulinemia, X-linked 1 PMID:34975878 [Fam.F215:P215]
101774 M 210908tree icon - Argentinian Decreased proportion of switched memory B cells Adenosine deaminase 2 deficiency PMID:28493328 [P9(II.1)]
101788 M 210950tree icon - Swiss Decreased proportion of switched memory B cells Adenosine deaminase 2 deficiency PMID:28493328 [P7(II.1)]
101789 M 210950tree icon - Swiss Decreased proportion of switched memory B cells Adenosine deaminase 2 deficiency PMID:28493328 [Fam.P7:II.2(P8)]
101794 F 211030 - Italian Decreased proportion of switched memory B cells Adenosine deaminase 2 deficiency PMID:28493328 [P5]
101798 M 211117 45 Decreased proportion of switched memory B cells Adenosine deaminase 2 deficiency PMID:28493328 [P11]
101802 F 211221tree icon 38 German Decreased proportion of switched memory B cells NFKB1 insufficiency PMID:33995346 [Fam.A:III.2(Pat2)]; PMID:150198 [Fam.DV:III.2(528)]; PMID:36105815 [Fam.Y350C:III.2(Y350C/2)]
101803 F 211221tree icon - German Decreased proportion of switched memory B cells NFKB1 insufficiency PMID:33995346 [Fam.A:II.2(Pat1)]; PMID:150198 [Fam.DV:II.2(521)]; PMID:36105815 [Fam.Y350C:II.2(Y350C/1)]
101813 F 211525 52,52 Abnormal B cell count,Decreased proportion of switched memory B cells PMID:34975878 [Fam.F273:P273]
101827 M 211564 28 Decreased proportion of switched memory B cells PMID:34975878 [Fam.F291:P291]
101925 M 210095 - Indian Decreased proportion of memory B cells Hyper-IgE recurrent infection syndrome 1 PMID:34390440 [CMC20]; PMID:28667753 [case]
102138 M 214393tree icon 62 North American Decreased proportion of switched memory B cells Immunodeficiency, common variable, 14 PMID:27016798 [Fam.Patient:II.2(F)]; PMID:37876937 [Fam.A:II.1(A.3)]
102141 F 214393tree icon 18 North American Decreased proportion of switched memory B cells Immunodeficiency, common variable, 14 PMID:27016798 [Patient(III.1)]; PMID:37876937 [Fam.A:III.1(A.1)]
102142 M 214393tree icon 22 North American Decreased proportion of switched memory B cells Immunodeficiency, common variable, 14 PMID:27016798 [Fam.Patient:III.2(B)]; PMID:37876937 [Fam.A:III.2(A.2)]
102168 M 214767tree icon 3 Georgian Decreased proportion of switched memory B cells Agammaglobulinemia 14 PMID:33571536 [P-FR1(II.3)]
102410 F 214947tree icon 5 South Asian Decreased proportion of switched memory B cells Hyper-IgE recurrent infection syndrome 4B PMID:28747427 [Fam.A:II.3(P1)]
102466 M 214962tree icon 5 Polish Decreased proportion of switched memory B cells Immunodeficiency 94 PMID:33517393 [Patient(III.7)]
102731 F 214982tree icon 8,- Colombian Decreased proportion of memory B cells,Decreased proportion of switched memory B cells Immunodeficiency 99 PMID:32484799 [Patient(II.2)]
102865 F 214996tree icon 7,- Italian Decreased proportion of memory B cells,Decreased proportion of switched memory B cells ARPC1B deficiency | Hartnup disease PMID:35967303 [PtII-1(II.1)]; PMID:35967303 [PtII-1(II.1)]
102984 F 215074tree icon - European/American Decreased proportion of memory B cells Immunodeficiency 97 PMID:31554793 [A.1(II.1)]
103062 M 215096tree icon 7 Finnish Decreased proportion of switched memory B cells Seizures, cortical blindness, microcephaly syndrome PMID:33662367 [Fam.F2:II.2(P3)]
103067 F 215097tree icon 3 Finnish Decreased proportion of switched memory B cells Seizures, cortical blindness, microcephaly syndrome PMID:33662367 [Fam.F3:II.3(P4)]
103072 F 215098tree icon 25 Finnish Decreased proportion of switched memory B cells Seizures, cortical blindness, microcephaly syndrome PMID:33662367 [Fam.F4:II.1(P5)]
103110 M 215099tree icon 3 Omani Decreased proportion of switched memory B cells Seizures, cortical blindness, microcephaly syndrome PMID:33662367 [Fam.F5:V.2(P7)]
103293 M 215115 44 Decreased proportion of switched memory B cells Immunodeficiency 82 with systemic inflammation PMID:33782605 [P6]
103830 F 215256tree icon - European Decreased proportion of memory B cells Adenosine deaminase 2 deficiency PMID:24552284 [Fam.1:II.2(P1)]
103834 F 215257tree icon - European Decreased proportion of memory B cells Adenosine deaminase 2 deficiency PMID:24552284 [Fam.2:II.3(P2)]
103839 M 215258tree icon - European Decreased proportion of memory B cells Adenosine deaminase 2 deficiency PMID:24552284 [Fam.3:II.3(P3)]
103848 M 215260tree icon - European Decreased proportion of memory B cells Adenosine deaminase 2 deficiency PMID:24552284 [Fam.5:II.1(P5)]
104410 M 215525tree icon 1 Japanese Decreased proportion of switched memory B cells Early-onset atopic inflammation PMID:36538978 [Patient(II.2)]
104414 M 215526tree icon 8 Turkish Decreased proportion of memory B cells Early-onset atopic inflammation PMID:36758835 [Patient(V.3)]
104534 M 215546tree icon - Caucasian Decreased proportion of switched memory B cells X-linked multisystem autoinflammatory disease with immune dysregulation PMID:36952639 [Fam.C:II.1(Patient C)]
104541 M 215550tree icon - North African Decreased proportion of switched memory B cells X-linked multisystem autoinflammatory disease with immune dysregulation PMID:36952639 [Fam.G:II.1(Patient G)]
104842 M 215579tree icon 50 European Decreased proportion of switched memory B cells NFKB1 insufficiency PMID:32278790 [Fam.NZ:II.1(II.1)]; PMID:26279205 [Fam.NZ:II.1(II1)]; PMID:29403474 [Fam.NZ (5):II.1(II1)]; PMID:29806948 [Fam.NZ:II.1(II.1)]; PMID:30323807 [Fam.2:II.1(II.1)]; PMID:150198 [Fam.AC:II.1(108)]
104844 F 215579tree icon 76 European Decreased proportion of switched memory B cells NFKB1 insufficiency PMID:32278790 [Fam.NZ:I.2(I.2)]; PMID:26279205 [Fam.NZ:I.2(I2)]; PMID:29403474 [Fam.NZ (5):I.2(I2)]; PMID:29806948 [Fam.NZ:I.2(I.2)]; PMID:30323807 [Fam.2:I.2(I.2)]; PMID:150198 [Fam.AC:I.2(107)]
104875 M 215579tree icon 46 European Decreased proportion of switched memory B cells NFKB1 insufficiency PMID:32278790 [Fam.NZ:II.3(II.3)]; PMID:26279205 [Fam.NZ:II.3(II3)]; PMID:29806948 [Fam.NZ:II.3(II.3)]; PMID:30323807 [Fam.2:II.3(II.3)]; PMID:150198 [Fam.AC:II.3(110)]
104876 F 215579tree icon 15 European Decreased proportion of switched memory B cells NFKB1 insufficiency PMID:32278790 [Fam.NZ:III.1(III.1)]; PMID:26279205 [Fam.NZ:III.1(III1)]; PMID:29806948 [Fam.NZ:III.1(III.1)]; PMID:30323807 [Fam.2:III.1(III.1)]; PMID:150198 [Fam.AC:III.1(112)]
104923 M 215620tree icon - Decreased proportion of switched memory B cells Immunodeficiency, common variable, 14 PMID:36193988 [Patient(II.1)]; PMID:37876937 [Fam.D:II.1(D.1)]
104972 F 215622tree icon 55 Dutch Decreased proportion of switched memory B cells NFKB1 insufficiency PMID:32278790 [Fam.NA:III.14(III.14)]; PMID:26279205 [Fam.NL1:III.14(36)]; PMID:29403474 [Fam.NL1 (5):III.14(36)]; PMID:11583829 [Fam.1:III.14(III:14)]; PMID:16639407 [Fam.1:III.14(36)]; PMID:27923702 [Patient 4]; PMID:27555455 [Patient 2]; PMID:150198 [Fam.AA:III.14(040)]
105019 M 215624tree icon - French Decreased proportion of memory B cells Hyper-IgE recurrent infection syndrome 1 PMID:31346092 [P1(III.4)]
105065 M 215624tree icon - French Decreased proportion of memory B cells Hyper-IgE recurrent infection syndrome 1 PMID:31346092 [Fam.P1:III.5(P7)]
105066 F 215624tree icon - French Decreased proportion of memory B cells Hyper-IgE recurrent infection syndrome 1 PMID:31346092 [Fam.P1:III.6(P3)]
105131 M 215648 40 Italian Decreased proportion of switched memory B cells NFKB1 insufficiency PMID:32278790 [BG.I.1]; PMID:29403474 [Patient 1 (6)]; PMID:27923702 [Patient 1]; PMID:27555455 [Patient 1]; PMID:150198 [Fam.AN:160]
105152 F 215655tree icon - Spanish Decreased proportion of switched memory B cells NFKB1 insufficiency PMID:32278790 [V.I.1]; PMID:29403474 [Patient 26 (11)]; PMID:150198 [Fam.AK:I.2(149)]; PMID:27461466 [Fam.827_01:26]
105197 M 215666tree icon 37 Finnish Decreased proportion of switched memory B cells NFKB1 insufficiency PMID:32278790 [Fam.F1:III.3(III.3)]; PMID:29403474 [Fam.1 (9):III.3(F1.III-3)]; PMID:28115215 [Fam.1:III.3(F1.III-3)]; PMID:150198 [Fam.AQ:III.3(177)]; PMID:36356849 [Fam.6:III.3(F6:III:3)]; PMID:36105815 [Fam.H67R:III.3(H67R/4)]
105212 F 215666tree icon 55 Finnish Decreased proportion of switched memory B cells NFKB1 insufficiency PMID:32278790 [Fam.F1:II.4(II.4)]; PMID:29403474 [Fam.1 (9):II.4(F1.II-4)]; PMID:28115215 [Fam.1:II.4(F1.II-4)]; PMID:150198 [Fam.AQ:II.4(174)]; PMID:36356849 [Fam.6:II.4(F6:II:4)]; PMID:36105815 [Fam.H67R:II.4(H67R/2)]
105214 F 215666tree icon 40 Finnish Decreased proportion of switched memory B cells NFKB1 insufficiency PMID:32278790 [Fam.F1:III.2(III.2)]; PMID:29403474 [Fam.1 (9):III.2(F1.III-2)]; PMID:28115215 [Fam.1:III.2(F1.III-2)]; PMID:150198 [Fam.AQ:III.2(176)]; PMID:36356849 [Fam.6:III.2(F6:III:2)]; PMID:36105815 [Fam.H67R:III.2(H67R/3)]
105221 M 215666tree icon 10 Finnish Decreased proportion of switched memory B cells NFKB1 insufficiency PMID:32278790 [Fam.F1:IV.2(IV.2)]; PMID:28115215 [Fam.1:IV.1(F1.IV-1)]; PMID:150198 [Fam.AQ:IV.1(183)]; PMID:36356849 [Fam.6:IV.1(F6:IV:1)]; PMID:36105815 [Fam.H67R:IV.1(H67R/8)]
105222 F 215666tree icon 7 Finnish Decreased proportion of switched memory B cells NFKB1 insufficiency PMID:32278790 [Fam.F1:IV.1(IV.1)]; PMID:29403474 [Fam.1 (9):IV.2(F1.IV-2)]; PMID:28115215 [Fam.1:IV.2(F1.IV-2)]; PMID:150198 [Fam.AQ:IV.2(184)]; PMID:36356849 [Fam.6:IV.2(F6:IV:2)]; PMID:36105815 [Fam.H67R:IV.2(H67R/9)]
105225 F 215671tree icon 61 Finnish Decreased proportion of switched memory B cells NFKB1 insufficiency PMID:32278790 [Fam.F2:II.2(II.2)]; PMID:29403474 [Fam.2 (9):II.3(F2.II-3)]; PMID:28115215 [Fam.2:II.3(F2.II-3)]; PMID:150198 [Fam.AR:II.3(191)]; PMID:36356849 [Fam.5:II.2(F5:II:2)]
105231 M 215671tree icon 32 Finnish Decreased proportion of switched memory B cells NFKB1 insufficiency PMID:32278790 [Fam.F2:III.2(III.2)]; PMID:29403474 [Fam.2 (9):III.2(F2.III-2)]; PMID:28115215 [Fam.2:III.2(F2.III-2)]; PMID:150198 [Fam.AR:III.2(193)]; PMID:36356849 [Fam.5:III.2(F5:III:2)]
105232 M 215672tree icon 62 Finnish Decreased proportion of switched memory B cells NFKB1 insufficiency PMID:32278790 [Fam.F3:II.1(II.1)]; PMID:29403474 [Fam.3 (9):II.1(F3.II-1)]; PMID:28115215 [Fam.3:II.1(F3.II-1)]; PMID:150198 [Fam.AS:II.1(196)]; PMID:36356849 [Fam.3:II.1(F3:II:1)]; PMID:36892687 [II:1(II.1)]; PMID:38593810 [Fam.1:II.1(F1.II-1)]
105238 M 215672tree icon 56 Finnish Decreased proportion of switched memory B cells NFKB1 insufficiency PMID:32278790 [Fam.F3:II.5(II.5)]; PMID:29403474 [Fam.3 (9):II.5(F3.II-5)]; PMID:28115215 [Fam.3:II.5(F3.II-5)]; PMID:150198 [Fam.AS:II.9(204)]; PMID:36356849 [Fam.3:II.9(F3:II:9)]; PMID:36892687 [II:5(II.5)]; PMID:38593810 [Fam.1:II.9(F1.II-5)]
105245 M 215674tree icon - Caucasian Decreased proportion of switched memory B cells NFKB1 insufficiency PMID:32278790 [Fam.AN:II.2(II.1)]; PMID:29403474 [Fam.(12):I.1(P9.1)]; PMID:28983403 [Fam.1:I.1(P9.1)]; PMID:150198 [Fam.AT:II.1(223)]
105246 M 215674tree icon - Caucasian Decreased proportion of switched memory B cells NFKB1 insufficiency PMID:32278790 [Fam.AN:III.2(III.1)]; PMID:29403474 [Fam.(12):II.1(P9.2)]; PMID:28983403 [Fam.1:II.1(P9.2)]; PMID:150198 [Fam.AT:III.2(226)]
105279 F 215685tree icon - European Decreased proportion of switched memory B cells NFKB1 insufficiency PMID:32278790 [Fam.B:II.1(II.1)]; PMID:29477724 [Fam.B:II.1(II:1)]; PMID:150198 [Fam.AV:II.1(244)]
105284 F 215640tree icon - European Decreased proportion of switched memory B cells NFKB1 insufficiency PMID:32278790 [Fam.A:II.1(II.1)]; PMID:29477724 [Fam.A:II.1(II:1)]; PMID:150198 [Fam.AU:II.2(230)]
105287 F 215640tree icon - European Decreased proportion of switched memory B cells NFKB1 insufficiency PMID:32278790 [Fam.A:II.4(II.4)]; PMID:29477724 [Fam.A:II.4(II:4)]; PMID:150198 [Fam.AU:II.5(233)]
105290 M 215640tree icon - European Decreased proportion of switched memory B cells NFKB1 insufficiency PMID:32278790 [Fam.A:III.2(III.2)]; PMID:29477724 [Fam.A:III.2(III:2)]; PMID:150198 [Fam.AU:III.2(235)]; PMID:32918165 [Fam.A:III.2(brother)]
105296 F 215686tree icon - European Decreased proportion of switched memory B cells NFKB1 insufficiency PMID:32278790 [Fam.C:I.2(I.2)]; PMID:29477724 [Fam.C:I.2(I:2)]; PMID:150198 [Fam.AW:I.2(246)]
105304 F 215686tree icon - European Decreased proportion of switched memory B cells NFKB1 insufficiency PMID:32278790 [Fam.C:III.1(III.1)]; PMID:29477724 [Fam.C:III.1(III:1)]; PMID:150198 [Fam.AW:III.1(253)]
105306 M 215686tree icon - European Decreased proportion of switched memory B cells NFKB1 insufficiency PMID:32278790 [Fam.C:III.3(III.3)]; PMID:29477724 [Fam.C:III.3(III:3)]; PMID:150198 [Fam.AW:III.3(255)]
105307 M 215686tree icon - European Decreased proportion of switched memory B cells NFKB1 insufficiency PMID:32278790 [Fam.C:III.4(III.4)]; PMID:29477724 [Fam.C:III.4(III:4)]; PMID:150198 [Fam.AW:III.4(256)]
105308 F 215687tree icon - European Decreased proportion of switched memory B cells NFKB1 insufficiency PMID:32278790 [Fam.D:II.2(II.2)]; PMID:29477724 [Fam.D:II.2(II:2)]; PMID:150198 [Fam.AX:II.2(260)]
105311 F 215687tree icon - European Decreased proportion of switched memory B cells NFKB1 insufficiency PMID:32278790 [Fam.D:I.2(I.2)]; PMID:29477724 [Fam.D:I.2(I:2)]; PMID:150198 [Fam.AX:I.2(258)]
105313 M 215688tree icon - European Decreased proportion of switched memory B cells NFKB1 insufficiency PMID:32278790 [E.II.1]; PMID:29477724 [Fam.E:II.1(II:1)]; PMID:150198 [Fam.AY:II.2(264)]; PMID:36105815 [Fam.I281M:II.2(I281M/1)]
105317 M 215692tree icon - European Decreased proportion of switched memory B cells NFKB1 insufficiency PMID:32278790 [Fam.J:III.2(III.2)]; PMID:29477724 [Fam.J:III.2(III:2)]; PMID:150198 [Fam.BD:III.2(277)]
105337 U 215699 - European Decreased proportion of switched memory B cells NFKB1 insufficiency PMID:32278790 [I.II.1]; PMID:29477724 [Fam.I:II.1(I:II-1)]; PMID:150198 [Fam.BC:268]
105363 F 215722 13 Afro-American Decreased proportion of switched memory B cells CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.X:II.1(X.II.1 (59))]; PMID:28366794 [Fam.A:II.1(P1)]
105423 M 215765tree icon 3 Caucasian Decreased proportion of switched memory B cells NFKB1 insufficiency PMID:150198 [Fam.BO:II.2(308)]; PMID:30761159 [Fam.1:II.2(patient)]
105428 M 215766tree icon 3 Admixed Decreased proportion of switched memory B cells Adenosine deaminase 2 deficiency PMID:26867732 [Fam.F:II.2(P9)]; PMID:25457153 [Fam.1:II.3(P2)]; PMID:25075846 [Fam.1:II.3(younger-sib)]
105432 M 215767tree icon 33 Caucasian Decreased proportion of switched memory B cells NFKB1 insufficiency PMID:150198 [Fam.BR:II.1(316)]; PMID:31803180 [Fam.A:II.1(S1)]; PMID:34619682 [P.200]
105465 M 215772tree icon 32 Russian Decreased proportion of switched memory B cells NFKB1 insufficiency PMID:150198 [Fam.BS:II.1(319)]; PMID:31803180 [Fam.B:II.1(S3)]
105466 M 215772tree icon 23 Russian Decreased proportion of switched memory B cells NFKB1 insufficiency PMID:150198 [Fam.BS:II.2(320)]; PMID:31803180 [Fam.B:II.2(S4)]
105475 F 215776tree icon - European Decreased proportion of switched memory B cells Ezrin immunodeficiency PMID:37301410 [P1(II.4)]
105481 M 215777tree icon - Haitian/Hispanic Decreased proportion of switched memory B cells Activated p110-delta syndrome 1 PMID:24165795 [Fam.A:II.1(A.1)]
105484 F 215778tree icon - Caucasian Decreased proportion of switched memory B cells Activated p110-delta syndrome 1 PMID:24165795 [Fam.B:III.1(B.III.1)]
105487 F 215780tree icon - Afro-American Decreased proportion of switched memory B cells Activated p110-delta syndrome 1 PMID:24165795 [Fam.G:II.1(G.1)]
105504 F 215783tree icon - Asian Decreased proportion of switched memory B cells Activated p110-delta syndrome 1 PMID:24165795 [Fam.E:II.1(E.1)]
105509 M 215784tree icon - Caucasian Decreased proportion of switched memory B cells Activated p110-delta syndrome 1 PMID:24165795 [Fam.D:II.1(D.II.1)]
105513 F 215787tree icon - Caucasian Decreased proportion of switched memory B cells Activated p110-delta syndrome 1 PMID:24165795 [Fam.F:II.1(F.II.1)]
105549 F 215801 12 Caucasian Decreased proportion of memory B cells CTLA4 haploinsufficiency with autoimmune infiltration PMID:29200144 [Fam.A:IV.1(P1)]
105571 U 215810 5 Decreased proportion of memory B cells Activated p110-delta syndrome 1 PMID:24698326 [P3]
105575 U 215814 11 Decreased proportion of switched memory B cells Activated p110-delta syndrome 1 PMID:24698326 [P6]
105623 M 215822 13 Caucasian Decreased proportion of memory B cells Activated p110-delta syndrome 1 PMID:25352054 [Fam.1:II.6(P2)]
105626 M 215822 - Caucasian Decreased proportion of switched memory B cells Activated p110-delta syndrome 1 PMID:25352054 [Fam.1:III.1(P3)]
105627 F 215822 3 Caucasian Decreased proportion of switched memory B cells Activated p110-delta syndrome 1 PMID:25352054 [Fam.1:III.2(P4)]
105628 F 215822 3 Caucasian Decreased proportion of memory B cells Activated p110-delta syndrome 1 PMID:25352054 [Fam.1:III.3(P5)]
105635 F 215829 - Caucasian Decreased proportion of memory B cells Activated p110-delta syndrome 1 PMID:26371693 [1]
105659 F 215836 - Decreased proportion of switched memory B cells Activated p110-delta syndrome 1 PMID:26437962 [Fam.A:II.2(Sibling 2)]
105660 F 215836 - Decreased proportion of switched memory B cells Activated p110-delta syndrome 1 PMID:26437962 [Fam.A:II.3(Sibling 3)]
105757 F 215860 - North American Decreased proportion of switched memory B cells NFKB1 insufficiency PMID:32278790 [BJ.I.1]; PMID:150198 [Fam.CX:443]
105778 F 215871tree icon 8 Spanish Decreased proportion of switched memory B cells NFKB1 insufficiency PMID:32278790 [CB.I.1]; PMID:150198 [Fam.DM:II.1(472)]; PMID:36105815 [Fam.G386R:II.1(G386R/1)]
105791 F 215877tree icon - Spanish Decreased proportion of switched memory B cells Immunodeficiency, common variable, 14 PMID:37876937 [Fam.1:II.1(1.1)]
105793 M 215877tree icon - Spanish Decreased proportion of switched memory B cells Immunodeficiency, common variable, 14 PMID:37876937 [Fam.1:I.2(1.2)]
105839 M 215888tree icon - Romani Decreased proportion of switched memory B cells Immunodeficiency, common variable, 14 PMID:37876937 [Fam.3:II.1(3.1)]
105943 M 215912tree icon 20 Colombian/Swiss Decreased proportion of memory B cells Hyper-IgE recurrent infection syndrome 4A PMID:37273120 [Fam.C:II.1(P8)]
106304 M 215981tree icon 54 Chinese (China) Decreased proportion of switched memory B cells NFKB1 insufficiency PMID:150198 [Fam.FO:II.5(717)]; PMID:36571238 [Fam.1:II.5(II:5[P1])]
106312 M 215981tree icon 29 Chinese (China) Decreased proportion of switched memory B cells NFKB1 insufficiency PMID:150198 [Fam.FO:III.1(719)]; PMID:36571238 [Fam.1:III.1(III:1[P2])]
106393 F 216006tree icon - German Decreased proportion of switched memory B cells CTLA4 haploinsufficiency with autoimmune infiltration PMID:36273440 [III.3(III.3)]
106409 M 216010tree icon 42 Chinese (China) Decreased proportion of switched memory B cells NFKB1 insufficiency PMID:150198 [Fam.FT:II.2(741)]; PMID:37775675 [Fam.1:II.2(patient)]
106463 F 216023tree icon - Japanese Decreased proportion of switched memory B cells NFKB1 insufficiency PMID:150198 [Fam.FX:II.3(779)]; PMID:38514645 [Fam.1:II.3(proband)]
106470 F 216023tree icon 3 Japanese Decreased proportion of switched memory B cells NFKB1 insufficiency PMID:150198 [Fam.FX:III.1(781)]; PMID:38514645 [Fam.1:III.1(III:1)]
106592 M 216085 16,16 Decreased proportion of memory B cells,Decreased proportion of switched memory B cells CTLA4 haploinsufficiency with autoimmune infiltration PMID:34116213 [Fam.A:II.1(P1)]
106610 F 216089tree icon - Australian Decreased proportion of switched memory B cells Agammaglobulinemia 8A | Immunodeficiency, common variable, 2 PMID:30323807 [Fam.1:II.2(II.2)]; PMID:30323807 [Fam.1:II.2(II.2)]; PMID:29114388 [Fam.A:II.2(II.2)]; PMID:29114388 [Fam.A:II.2(II.2)]
106615 M 216089tree icon - Australian Decreased proportion of switched memory B cells Immunodeficiency, common variable, 2 PMID:30323807 [Fam.1:II.4(II.4)]; PMID:29114388 [Fam.A:II.4(II.4)]
106616 M 216089tree icon - Australian Decreased proportion of switched memory B cells Agammaglobulinemia 8A PMID:30323807 [Fam.1:III.1(III.1)]; PMID:29114388 [Fam.A:III.1(III.1)]
106625 F 216092tree icon - Admixed Decreased proportion of memory B cells Autoinflammation, immune dysregulation, and eosinophilia PMID:38563820 [Fam.5:II.2(P13)]
106637 M 216096tree icon - Danish Decreased proportion of switched memory B cells Infantile-Onset Multisystem Autoimmune Disease 1 PMID:32047491 [P3(II.1)]
106646 M 216099 22 Decreased proportion of switched memory B cells CTLA4 haploinsufficiency with autoimmune infiltration PMID:34628649 [Patient(III.1)]
106794 F 216145tree icon 27 German Decreased proportion of switched memory B cells Immunodeficiency, common variable, 14 PMID:34619682 [P.263]; PMID:39059757 [Fam.1:II.2(P2)]
106807 F 216145tree icon 16 German Decreased proportion of switched memory B cells Immunodeficiency, common variable, 14 PMID:34619682 [P.159]; PMID:39059757 [Fam.1:II.1(P1)]
106812 F 216158 31 Decreased proportion of switched memory B cells Immunodeficiency, common variable, 14 PMID:39059757 [P4]
106819 M 216163tree icon 54 Chinese (China) Decreased proportion of switched memory B cells Immunodeficiency, common variable, 1 PMID:36571238 [Fam.2:II.2(II:2[P3])]
106953 M 216195 - Decreased proportion of switched memory B cells NFKB1 insufficiency PMID:150198 [Fam.GA:793]; PMID:38901617 [Fam.1:I.1(P1)]
107156 F 216365tree icon 10 Turkish Decreased proportion of switched memory B cells Hyper-IgE recurrent infection syndrome 2 PMID:39437980 [Fam.B:II.2(Patient 2)]

*Age: age reported at the first known time of manifestation; PMID: PubMed ID; GRID: GenIA reference ID (ref. not in PubMed).