Decreased lymphocyte proliferation in response to mitogens

Basic details

Preferred term: Decreased lymphocyte proliferation in response to mitogens
Alt. terms: Reduced lymphocyte proliferation to mitogens

HPO term: Decreased lymphocyte proliferation in response to mitogen
HPO code: HP:0031381

GenIA ID: 11760
Last updated on: 2024-04-11 11:51:19

Cross ref. with other ontologies

NCIT: -
MESH: -
EFO: -
OAE: -
SNOMEDCT: -
ICD10: -

Description

A decreased proliferative response of lymphocytes in vitro or in vivo, when stimulated with mitogens, such as phytohemagglutinin (PHA, anti-CD3, PWM, etc).

Hierarchical classification

Reported patients added to GenIA DB

SubjectID Sex Fam.ID Age* Population MatchedTerm Diagnosis Reference & Pub.codes
101015 M 210203 - German Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:30250467 [Fam.MM:II.1]; PMID:29729943 [Fam.MM:II.1(87)]; PMID:34975878 [Fam.F002:P002]; PMID:31857261 [Patient 3]
101037 M 210182tree icon - Caucasian Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:25329329 [Fam.B:II.4(B.II.3)]; PMID:30250467 [B.II.3]; PMID:29729943 [Fam.B:II.4(B.II.3 (15))]; PMID:27418640 [P13(5)]
101038 F 210182tree icon - Caucasian Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:25329329 [Fam.B:II.6(B.II.4)]; PMID:30250467 [B.II.4]; PMID:29729943 [Fam.B:II.6(B.II.4 (16))]; PMID:34975878 [Fam.F014:III.6(P015)]; PMID:27418640 [P14(5)]
101040 F 210724tree icon - Caucasian Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.GG:II.1(79)]; PMID:31857261 [Patient 15]
101043 M 210725tree icon - Caucasian Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.H:II.2(30)]; PMID:34975878 [Fam.F017:P017]
101045 M 210205tree icon - Caucasian Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:25329329 [Fam.A:III.13(A.III.3)]; PMID:29729943 [Fam.A:III.3(9)]; PMID:34975878 [Fam.F018:III.2(P018)]; PMID:27418640 [P11(5)]
101051 F 210205tree icon - Caucasian Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:25329329 [Fam.A:III.5(A.III.1)]; PMID:30250467 [A.III.1]; PMID:29729943 [Fam.A:III.5(A.III.1 (8))]; PMID:34975878 [Fam.F018:III.1(P021)]; PMID:27418640 [P10(5)]
101077 F 210211 - German Abnormal lymphoproliferation PMID:34975878 [Fam.F043:P043]
101091 M 210911 - Abnormal lymphoproliferation DiGeorge syndrome PMID:34975878 [Fam.F057:P057]; PMID:35486341 [P180]
101116 M 210282tree icon - German Abnormal lymphoproliferation Immunodeficiency, common variable, 1 PMID:12577056 [Fam.A:II.2(P2)]; PMID:16384931 [Fam.A:II.3(P2)]; PMID:19426217 [Fam.A:II.2(P2)]; PMID:28861081 [Fam.1:II.2(P2)]; PMID:35486341 [P005]
101118 F 210735 - Abnormal lymphoproliferation Thrombophilia due to Factor V Leiden PMID:31057532 [Fam.C:II.1]
101119 M 210264 - Abnormal lymphoproliferation PMID:34975878 [Fam.F070:P070]
101120 M 210221 - German Abnormal lymphoproliferation PMID:34975878 [Fam.F071:P071]
101122 M 210197tree icon 23 Italian Abnormal lymphoproliferation NFKB1 insufficiency PMID:34975878 [Fam.F073:P073]; PMID:150198 [Fam.DZ:II.2(548)]
101123 M 210255 - Abnormal lymphoproliferation PMID:34975878 [Fam.F074:P074]
101128 M 210897 - Caucasian Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.OO:II.1(95)]; PMID:37740092 [P07]
101145 M 211221tree icon 42 German Decreased lymphocyte proliferation in response to mitogen: SAC NFKB1 insufficiency PMID:33995346 [Fam.A:III.5(Pat4)]; PMID:150198 [Fam.DV:III.5(531)]; PMID:36105815 [Fam.Y350C:III.5(Y350C/4)]
101150 F 210736 7 Abnormal lymphoproliferation Immunodeficiency, common variable, 2 PMID:34975878 [Fam.F093:P093]
101155 M 210235 - German Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:30250467 [JJ.II.I]; PMID:29729943 [Fam.JJ:II.1(83)]; PMID:34975878 [Fam.F098:P098]
101199 F 211483 - German Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.YY:II.1(127)]; PMID:34975878 [Fam.F122:P122]
101286 F 212146 - Saudi Decreased lymphocyte proliferation in response to mitogen: anti-CD3 Immunodeficiency, common variable, 8 PMID:22721650 [Fam.VI:5:V.3]; PMID:25468195 [Fam.C:II.3(P4)]; PMID:26707784 [P8]
101287 F 212146 - Saudi Decreased lymphocyte proliferation in response to mitogen: anti-CD3 Immunodeficiency, common variable, 8 PMID:22721650 [Fam.VI:5:V.4]; PMID:25468195 [Fam.C:II.4(P5)]; PMID:26707784 [P9]
101288 F 212146 - Saudi Decreased lymphocyte proliferation in response to mitogen: anti-CD3 Immunodeficiency, common variable, 8 PMID:22721650 [Fam.VI:5:V.5]; PMID:25468195 [Fam.C:II.5(P6)]; PMID:26707784 [P10]
101336 M 212152 - Omani Abnormal lymphoproliferation Immunodeficiency, common variable, 8 PMID:28473463 [Fam.3 :II.1]
101401 F 210205tree icon - Caucasian Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:25329329 [Fam.A:II.17(A.II.9)]; PMID:29729943 [Fam.A:II.17(A.II.9 (6))]; PMID:27418640 [P9(5)]
101425 M 210205tree icon - Caucasian Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:25329329 [Fam.A:II.8(A.II.5)]; PMID:29729943 [Fam.A:II.8(A.II.5 (4))]; PMID:27418640 [P7(5)]
101458 F 210656tree icon - Georgian Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:25329329 [Fam.E:II.3(E.II.3)]; PMID:29729943 [Fam.E:II.3(E.II.3 (23))]; PMID:27418640 [P19(5)]
101578 M 210205tree icon - German Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:25329329 [Fam.A:II.14(A.II.8)]; PMID:29729943 [Fam.A:II.14(A.II.8 (5))]; PMID:27418640 [P8(5)]
101613 F 210737 6 Abnormal lymphoproliferation PMID:34975878 [Fam.F210:P210]
101717 F 210260tree icon - Caucasian Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:25329329 [Fam.C:II.3(C.II.3)]; PMID:29729943 [Fam.C:II.3(C.II.3 (19))]; PMID:27418640 [P16(5)]
101722 F 210261tree icon - Asian Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:25329329 [Fam.D:II.1(D.II.1)]; PMID:29729943 [Fam.D:II.1(D.II.1 (22))]; PMID:27418640 [P18(5)]
101744 F 210182tree icon - Caucasian Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:25329329 [Fam.B:III.2(B.III.2)]; PMID:29729943 [Fam.B:III.3(B.III.2 (17))]; PMID:27418640 [P15(5)]
101792 M 210991 - Caucasian Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.NN:II.11(NN.II.9(92))]
101797 M 211108 - Caucasian Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.QQ:II.1(97)]; PMID:34975878 [Fam.F258:P258]
101799 M 211120 - Caucasian Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:30250467 [Fam.XX:II.1]; PMID:29729943 [Fam.XX:II.1(126)]
101800 M 215769tree icon - Caucasian Abnormal lymphoproliferation NFKB1 insufficiency PMID:34975878 [Fam.F259:P259]; PMID:32278790 [Fam.AT:III.2(III.2)]; PMID:150198 [Fam.BT:IV.1(319)]; PMID:31803180 [Fam.C:III.1(III.1)]
101802 F 211221tree icon 38 German Decreased lymphocyte proliferation in response to mitogen: SAC NFKB1 insufficiency PMID:33995346 [Fam.A:III.2(Pat2)]; PMID:150198 [Fam.DV:III.2(528)]; PMID:36105815 [Fam.Y350C:III.2(Y350C/2)]
101803 F 211221tree icon 69 German Decreased lymphocyte proliferation in response to mitogen: SAC NFKB1 insufficiency PMID:33995346 [Fam.A:II.2(Pat1)]; PMID:150198 [Fam.DV:II.2(521)]; PMID:36105815 [Fam.Y350C:II.2(Y350C/1)]
101804 M 211221tree icon 4 German Decreased lymphocyte proliferation in response to mitogen: SAC NFKB1 insufficiency PMID:33995346 [Fam.A:IV.1(Pat3)]; PMID:150198 [Fam.DV:IV.1(533)]; PMID:36105815 [Fam.Y350C:IV.1(Y350C/3)]
102157 F 214681 - Caucasian Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.R:II.5(45)]
102175 M 210725tree icon - Caucasian Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:30250467 [Fam.H:II.1]; PMID:29729943 [Fam.H:II.1(29)]
102224 F 214919 - German Abnormal lymphoproliferation DiGeorge syndrome PMID:35486341 [P017]
102260 F 214926tree icon - Mexican Decreased lymphocyte proliferation in response to mitogens ARPC1B deficiency PMID:32683750 [Fam.case:II.2(sister)]; PMID:36708766 [Fam.A:II.2(P1)]
102637 M 214972tree icon 24 Abnormal lymphoproliferation Immunodeficiency 98 with autoinflammation, somatic PMID:33512449 [Fam.4:II.2(P4)]
102969 U 215061 0 North American Decreased lymphocyte proliferation in response to mitogens T-cell lymphopenia with or without nail dystrophy, AD PMID:31566583 [P4]; PMID:37419334 [P4]
102971 U 215063 0 North American Decreased lymphocyte proliferation in response to mitogens T-cell lymphopenia with or without nail dystrophy, AD PMID:31566583 [P6]; PMID:37419334 [P6]
102972 U 215064 1 North American Decreased lymphocyte proliferation in response to mitogens T-cell lymphopenia with or without nail dystrophy, AD PMID:31566583 [P7]; PMID:37419334 [P7]
102980 U 215072 0 North American Decreased lymphocyte proliferation in response to mitogens T-cell lymphopenia with or without nail dystrophy, AD PMID:31566583 [P15]; PMID:37419334 [P15]
103051 M 215095tree icon - Finnish Decreased lymphocyte proliferation in response to mitogens Seizures, cortical blindness, microcephaly syndrome PMID:33662367 [Fam.F1:II.7(P1)]
103061 M 215095tree icon - Finnish Decreased lymphocyte proliferation in response to mitogens Seizures, cortical blindness, microcephaly syndrome PMID:33662367 [Fam.F1:II.9(P2)]
103062 M 215096tree icon - Finnish Decreased lymphocyte proliferation in response to mitogens Seizures, cortical blindness, microcephaly syndrome PMID:33662367 [Fam.F2:II.2(P3)]
103076 F 215099tree icon 2 Omani Decreased lymphocyte proliferation in response to mitogens Seizures, cortical blindness, microcephaly syndrome PMID:33662367 [Fam.F5:V.5(P6)]
103110 M 215099tree icon 3 Omani Decreased lymphocyte proliferation in response to mitogens Seizures, cortical blindness, microcephaly syndrome PMID:33662367 [Fam.F5:V.2(P7)]
104540 M 215549tree icon - North African Abnormal lymphoproliferation X-linked multisystem autoinflammatory disease with immune dysregulation PMID:36952639 [Fam.F:II.1(Patient F)]
104787 M 215573tree icon - Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:25213377 [Fam.A:I.1(A.I.1)]; PMID:27418640 [P1(4)]
104791 M 215575tree icon - Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:25213377 [Fam.C:II.1(C.II.1)]; PMID:27418640 [P4(4)]
104838 M 215578tree icon - Caucasian Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:25329329 [Fam.F:II.2(F.II.2)]; PMID:29729943 [Fam.F:F.II.1 (24)]; PMID:27418640 [P20(5)]; PMID:34619682 [P.56]
104847 M 215581 0 Egyptian Abnormal lymphoproliferation Omenn syndrome 2 PMID:30307608 [2]
104850 M 215584 0 Egyptian Abnormal lymphoproliferation Omenn syndrome 2 PMID:30307608 [5]
104851 M 215585 0 Egyptian Abnormal lymphoproliferation Omenn syndrome 3 PMID:30307608 [6]
104858 M 215592 1 Egyptian Abnormal lymphoproliferation Severe combined immunodeficiency 9B, T-B- PMID:30307608 [11]
104879 F 215606 0 Egyptian Abnormal lymphoproliferation Severe combined immunodeficiency 9A, T-B- PMID:30307608 [25]
104886 F 215613tree icon - Caucasian Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.G:III.1(G.III.1 (26))]; PMID:25367873 [Fam.1:III.6(III.6)]
104916 M 215613tree icon - Caucasian Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:30250467 [G.III.2]; PMID:29729943 [Fam.G:III.2(G.III.2 (27))]; PMID:25367873 [Fam.1:III.5(III.5)]
105043 F 215630tree icon - Caucasian Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:27379089 [P9(II.1)]; PMID:29729943 [Fam.BBB:II.1(BBB.II.1 (131))]
105046 M 215632tree icon 6 Abnormal lymphoproliferation Infantile-Onset Multisystem Autoimmune Disease 1 PMID:28253502 [Fam.1:II.1(Patient 1)]
105057 F 215635tree icon 26 German Abnormal lymphoproliferation NFKB1 insufficiency PMID:32278790 [S.I.1]; PMID:29403474 [Patient 1 (8)]; PMID:27365489 [Fam.1:II.1(Pat.1)]; PMID:150198 [Fam.AE:II.1(121)]
105172 M 215659 - Caucasian Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.T:II.1(T.II.1 (48))]; PMID:27102614 [Fam.A:II.1(1)]
105175 M 215660 - Caucasian Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.Q:II.1(Q.II.1 (44))]; PMID:27102614 [Fam.B:I.1(2)]
105176 F 215661 - Caucasian Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.L:II.1(L.II.1 (35))]; PMID:27102614 [Fam.C:II.1(3)]
105177 M 215661 - Caucasian Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:30250467 [L.II.2]; PMID:29729943 [Fam.L:II.2(L.II.2 (36))]; PMID:27102614 [Fam.C:II.2(4)]
105179 F 215661 - Caucasian Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.L:I.2(L.I.2 (34))]; PMID:27102614 [Fam.C:I.2(mother)]
105180 M 215662 - Caucasian Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.S:II.1(S.II.1 (47))]; PMID:27102614 [Fam.D:II.1(5)]
105249 M 215676 3 Turkish Abnormal lymphoproliferation Immunodeficiency, common variable, 8 PMID:28956255 [Fam.P2:II.2]
105313 M 215688tree icon 7 European Abnormal lymphoproliferation NFKB1 insufficiency PMID:32278790 [E.II.1]; PMID:29477724 [Fam.E:II.1(II:1)]; PMID:150198 [Fam.AY:II.2(264)]; PMID:36105815 [Fam.I281M:II.2(I281M/1)]
105336 M 215698 - Caucasian Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.AAA:II.1(AAA.II.1 (130))]; PMID:27908448 [Patient(I.1)]
105363 F 215722 - Afro-American Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.X:II.1(X.II.1 (59))]; PMID:28366794 [Fam.A:II.1(P1)]
105370 F 215725 - Caucasian Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.Z:III.1(Z.III.1 (67))]; PMID:27577878 [Fam.B:II.1(15.1)]
105388 M 215739 - Abnormal lymphoproliferation Immunodeficiency, common variable, 8 PMID:31238161 [Fam.F1:P1]
105424 M 215766tree icon - Admixed Abnormal lymphoproliferation Adenosine deaminase 2 deficiency PMID:26867732 [Fam.F:II.1(P8)]; PMID:25457153 [Fam.1:II.2(P1)]; PMID:25075846 [Fam.1:II.2(older-sib)]
105428 M 215766tree icon - Admixed Abnormal lymphoproliferation Adenosine deaminase 2 deficiency PMID:26867732 [Fam.F:II.2(P9)]; PMID:25457153 [Fam.1:II.3(P2)]; PMID:25075846 [Fam.1:II.3(younger-sib)]
105533 M 215791 - Portuguese Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:29225858 [Patient(I.1)]
105546 M 215800tree icon - Caucasian Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:29867916 [N211(II.1)]; PMID:29729943 [Fam.O:II.1(O.II.1 (42))]
105564 M 215807tree icon 3 Spanish Abnormal lymphoproliferation 4q24 deletion syndrome PMID:29867916 [N227(II.1)]; PMID:150198 [Fam.BK:I.2(291)]; PMID:35784294 [case(II.1)]
105635 F 215829 9 Caucasian Abnormal lymphoproliferation Activated p110-delta syndrome 1 PMID:26371693 [1]
105750 M 215853 16 North American Abnormal lymphoproliferation NFKB1 insufficiency PMID:32278790 [AP.I.1]; PMID:150198 [Fam.CQ:436]
105773 M 215866 63 German Abnormal lymphoproliferation NFKB1 insufficiency PMID:32278790 [BU.I.1]; PMID:150198 [Fam.DF:463]; PMID:36105815 [A245V]
105859 F 215894tree icon 46 British Abnormal lymphoproliferation Immunodeficiency, common variable, 2 | NFKB1 insufficiency PMID:150198 [Fam.EA:I.2(551)]; PMID:150198 [Fam.EA:I.2(551)]; PMID:34922003 [Fam.A:I.2(A1)]; PMID:34922003 [Fam.A:I.2(A1)]
105899 F 215900tree icon 4 North American Abnormal lymphoproliferation NFKB1 insufficiency PMID:150198 [Fam.DW:II.1(538)]; PMID:34307247 [Fam.1:II.1(daughter1)]; PMID:28802957 [Fam.1:II.1(II.1)]
105907 M 215904 - Caucasian Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.J:II.1(J.II.1 (32))]
105910 F 215905 - Caucasian Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:30250467 [K.II.1]; PMID:29729943 [Fam.K:II.1(K.II.1 (33))]
105926 M 215909 - Japanese Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.N:III.2(N.III.2 (41))]; PMID:35087518 [Fam.12:III.2(12.4)]
105957 M 215914 - Caucasian Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.P:II.2(P.II.2 (43))]
105973 F 215917 - Japanese Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.V:II.1(V.II.1 (53))]; PMID:35087518 [14.1]
105974 M 215918 - Japanese Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.W:I.1(W.I.1 (54))]; PMID:30048690 [Fam.2:I.1(P2.1)]; PMID:35087518 [Fam.15:I.1(15.1)]
105976 M 215918 - Japanese Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.W:II.1(W.II.1 (55))]; PMID:35087518 [Fam.15:II.1(15.2)]
105977 F 215918 - Japanese Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.W:II.2(W.II.2 (56))]; PMID:30048690 [Fam.2:II.2(P2.2)]; PMID:35087518 [Fam.15:II.2(15.3)]
105978 F 215918 - Japanese Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.W:II.3(W.II.3 (57))]; PMID:30048690 [Fam.2:II.3(P2.3)]; PMID:35087518 [Fam.15:II.3(15.4)]
105981 M 215919 - Caucasian Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.Y:II.1(Y.II.1 (61))]
105985 F 215920 - Japanese Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.BB:II.2(BB.II.2 (72))]; PMID:30048690 [Fam.6:II.2(P6.2)]; PMID:35087518 [Fam.17:II.2(17.3)]
105986 F 215921tree icon 47 Abnormal lymphoproliferation NFKB1 insufficiency PMID:150198 [Fam.FG:II.2(630)]; PMID:36203612 [Fam.1:II.2(1.II.1)]
106000 M 215922tree icon - Abnormal lymphoproliferation NFKB1 insufficiency PMID:150198 [Fam.FH:III.2(641)]; PMID:36203612 [Fam.2:III.2(2.III.2)]
106023 M 215923 - Japanese Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.AA:IV.1(AA.IV.1 (69))]; PMID:30048690 [Fam.4:IV.1(P4.2)]; PMID:35087518 [Fam.16:IV.1(16.2)]
106036 F 215924 - Japanese Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.CC:II.1(CC.II.1 (73))]; PMID:30048690 [Fam.5:II.1(P5.1)]; PMID:35087518 [18.1]
106041 M 215926 - Caucasian Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.EE:II.1(EE.II.1 (76))]
106042 M 215927 - North American Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:30250467 [FF.II.1]; PMID:29729943 [Fam.FF:II.1(FF.II.1 (77))]
106044 F 215929 - Caucasian Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.KK:II.1(KK.II.1 (85))]
106047 F 215930 - Caucasian Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.LL:II.1(LL.II.1 (86))]
106057 F 210991 - Caucasian Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.NN:II.8(NN.II.6 (90))]
106060 F 210991 - Caucasian Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.NN:II.10(NN.II.8 (91))]
106068 M 215931 - Caucasian Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.PP:II.1(PP.II.1 (96))]
106069 F 215932 - Caucasian Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.RR:II.1(RR.II.1 (98))]
106070 F 215933 - Caucasian Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.SS:II.1(SS.II.1 (99))]
106094 M 215947 - Caucasian Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.VV:II.1(VV.II.1 (124))]
106097 M 215948 - Caucasian Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.WW:II.1(WW.II.1 (125))]
106099 M 210955 - Caucasian Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.ZZ:II.1(ZZ.II.1 (129))]
106105 M 215950 - Caucasian Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.CCC:II.1(CCC.II.1 (132))]
106109 M 215952tree icon - Iranian Abnormal lymphoproliferation NFKB1 insufficiency PMID:150198 [Fam.EG:III.4(584)]; PMID:35392793 [Fam.1:III.4(III-1(index))]
106246 F 215977 - Caucasian Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.UU:III.11(UU.III.7 (111))]; PMID:29305966 [Fam.IV.2:III.2(III.2)]
106251 M 215977 - Caucasian Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.UU:III.13(UU.III.9 (112))]; PMID:29305966 [Fam.IV.2:III.7(III.3)]
106259 F 215977 - Caucasian Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.UU:III.2(UU.III.2 (107))]; PMID:29305966 [Fam.IV.2:III.12(III.4)]
106313 F 215982 - Caucasian Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [P1]
106314 M 215983 - Caucasian Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [P2]
106371 M 216004 22 Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:29375547 [Fam.A:II.1(A.II.1)]; PMID:31396201 [P2(II.1)]
106555 M 216078tree icon - Caucasian Abnormal lymphoproliferation Adenosine deaminase 2 deficiency PMID:26867732 [Fam.A:II.1(P1)]; PMID:25075845 [Fam.1:II.2(Young-bro)]
106592 M 216085 16 Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:34116213 [Fam.A:II.1(P1)]
106636 F 216095 - Iranian Abnormal lymphoproliferation Activated p110-d syndrome 2 PMID:31117086 [P34]
106697 F 216110 - Japanese Abnormal lymphoproliferation CTLA4 haploinsufficiency with autoimmune infiltration PMID:30048690 [Fam.7:7.1]; PMID:35087518 [Fam.20:20.1]
106760 M 216123tree icon - Israeli Decreased lymphocyte proliferation in response to mitogen: anti-CD3 X-linked severe combined immunodeficiency PMID:32921793 [Fam.A:II.1(P1-A)]
106761 F 216124tree icon 1 Caucasian Decreased lymphocyte proliferation in response to mitogen: PHA T-negative/B-positive SCID type 1 PMID:28916186 [P5]; PMID:31440277 [pt(II.1)]
106812 F 216158 15 Abnormal lymphoproliferation Immunodeficiency, common variable, 14 PMID:39059757 [P4]
106819 M 216163tree icon - Chinese (China) Abnormal lymphoproliferation Immunodeficiency, common variable, 1 PMID:36571238 [Fam.2:II.2(II:2[P3])]
106912 F 216186 49 Abnormal lymphoproliferation Immunodeficiency, common variable, 8 PMID:39289195 [Patient(II.2)]
106956 M 216197 - Abnormal lymphoproliferation Infantile-Onset Multisystem Autoimmune Disease 1 PMID:30092289 [P12]

*Age: age reported at the first known time of manifestation; PMID: PubMed ID; GRID: GenIA reference ID (ref. not in PubMed).