Decreased specific antibody response to polysaccharide vaccine

Basic details

Preferred term: Decreased specific antibody response to polysaccharide vaccine
Alt. terms:

HPO term: Decreased specific antibody response to polysaccharide vaccine
HPO code: HP:0410299

GenIA ID: 15802
Last updated on: 2021-08-02 21:50:33

Cross ref. with other ontologies

NCIT: -
MESH: -
EFO: -
OAE: -
SNOMEDCT: -
ICD10: -

Description

A reduced ability to synthesize postvaccination antibodies against polysaccharides in vaccines, as measured by antibody titer determination following vaccination.

Hierarchical classification

Reported patients added to GenIA DB

SubjectID Sex Fam.ID Age* Population MatchedTerm Diagnosis Reference & Pub.codes
101015 M 210203 - German Absent ab-response to pneumococcal polysaccharide vaccine CTLA4 haploinsufficiency with autoimmune infiltration PMID:30250467 [Fam.MM:II.1]; PMID:29729943 [Fam.MM:II.1(87)]; PMID:34975878 [Fam.F002:P002]; PMID:31857261 [Patient 3]
101019 F 210316 - German Absent ab-response to pneumococcal polysaccharide vaccine PMID:34975878 [Fam.F004:P004]
101023 M 210731 34 German Negative ab-response to vaccination PMID:34975878 [Fam.F008:P008]
101045 M 210205tree icon - Caucasian Reduced ab-response to pneumococcal polysaccharide vaccine CTLA4 haploinsufficiency with autoimmune infiltration PMID:25329329 [Fam.A:III.13(A.III.3)]; PMID:29729943 [Fam.A:III.3(9)]; PMID:34975878 [Fam.F018:III.2(P018)]; PMID:27418640 [P11(5)]
101051 F 210205tree icon - Caucasian Reduced ab-response to pneumococcal polysaccharide vaccine CTLA4 haploinsufficiency with autoimmune infiltration PMID:25329329 [Fam.A:III.5(A.III.1)]; PMID:30250467 [A.III.1]; PMID:29729943 [Fam.A:III.5(A.III.1 (8))]; PMID:34975878 [Fam.F018:III.1(P021)]; PMID:27418640 [P10(5)]
101078 F 211301 51 Absent ab-response to pneumococcal polysaccharide vaccine PMID:34975878 [Fam.F044:P044]
101086 M 210934 - German Absent ab-response to pneumococcal polysaccharide vaccine PMID:34975878 [Fam.F052:P052]
101128 M 210897 - Caucasian Absent ab-response to pneumococcal polysaccharide vaccine CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.OO:II.1(95)]; PMID:37740092 [P07]
101129 F 210906 - German Absent ab-response to pneumococcal polysaccharide vaccine PMID:34975878 [Fam.F078:P078]
101132 M 210304 30 German Absent ab-response to pneumococcal polysaccharide vaccine PMID:34975878 [Fam.F081:P081]
101134 F 210901 - Absent ab-response to pneumococcal polysaccharide vaccine PMID:34975878 [Fam.F083:P083]
101143 F 211219 - Absent ab-response to pneumococcal polysaccharide vaccine PMID:34975878 [Fam.F088:P088]
101171 M 210012tree icon 7 Dutch Absent ab-response to pneumococcal polysaccharide vaccine Immunodeficiency, common variable, 20 PMID:25926555 [Patient(II.1)]
101199 F 211483 - German Reduced ab-response to pneumococcal polysaccharide vaccine CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.YY:II.1(127)]; PMID:34975878 [Fam.F122:P122]
101403 M 210189tree icon - German Absent ab-response to pneumococcal polysaccharide vaccine Adenosine deaminase 2 deficiency PMID:28493328 [P3]; PMID:26922074 [Index(II.2)]
101425 M 210205tree icon - Caucasian Reduced ab-response to pneumococcal polysaccharide vaccine CTLA4 haploinsufficiency with autoimmune infiltration PMID:25329329 [Fam.A:II.8(A.II.5)]; PMID:29729943 [Fam.A:II.8(A.II.5 (4))]; PMID:27418640 [P7(5)]
101458 F 210656tree icon - Georgian Reduced ab-response to pneumococcal polysaccharide vaccine CTLA4 haploinsufficiency with autoimmune infiltration PMID:25329329 [Fam.E:II.3(E.II.3)]; PMID:29729943 [Fam.E:II.3(E.II.3 (23))]; PMID:27418640 [P19(5)]
101461 M 210929 - German Absent ab-response to pneumococcal polysaccharide vaccine NFKB1 insufficiency PMID:34975878 [Fam.F153:P153]; PMID:32278790 [Z.I.1]; PMID:29403474 [Patient 27 (11)]; PMID:27923702 [Patient 6]; PMID:150198 [Fam.AL:151]; PMID:27461466 [Fam.830_01:27]
101504 F 211125 7 Absent ab-response to pneumococcal polysaccharide vaccine PMID:34975878 [Fam.F169:P169]
101543 F 210011 23 Absent ab-response to pneumococcal polysaccharide vaccine PMID:34975878 [Fam.F179:P179]
101553 M 210256 - German Absent ab-response to pneumococcal polysaccharide vaccine Infantile-Onset Multisystem Autoimmune Disease 1 PMID:34975878 [Fam.F182:P182]
101617 M 210994 - Absent ab-response to pneumococcal polysaccharide vaccine Immunodeficiency, common variable, 2 PMID:34975878 [Fam.F212:P212]
101723 F 210261tree icon - Asian Reduced ab-response to pneumococcal polysaccharide vaccine CTLA4 haploinsufficiency with autoimmune infiltration PMID:25329329 [Fam.D:I.2(D.I.2)]; PMID:29729943 [Fam.D:I.2(D.I.2 (21))]
101727 M 210300tree icon 45 North American Absent ab-response to pneumococcal polysaccharide vaccine Immunodeficiency, common variable, 15 PMID:28782633 [Fam.I:II.1(P1)]
101732 M 210300tree icon 15 North American Absent ab-response to pneumococcal polysaccharide vaccine Immunodeficiency, common variable, 15 PMID:28782633 [Fam.I:III.4(P3)]
101733 M 210300tree icon 16 North American Absent ab-response to pneumococcal polysaccharide vaccine Immunodeficiency, common variable, 15 PMID:28782633 [Fam.I:III.6(P4)]
101735 F 210300tree icon 13 North American Absent ab-response to pneumococcal polysaccharide vaccine Immunodeficiency, common variable, 15 PMID:28782633 [Fam.I:III.8(P5)]
101736 M 210300tree icon 11 North American Absent ab-response to pneumococcal polysaccharide vaccine Immunodeficiency, common variable, 15 PMID:28782633 [Fam.I:III.9(P6)]
101737 M 210300tree icon 16 North American Absent ab-response to pneumococcal polysaccharide vaccine Immunodeficiency, common variable, 15 PMID:28782633 [Fam.I:III.10(P7)]
101738 M 210300tree icon 13 North American Absent ab-response to pneumococcal polysaccharide vaccine Immunodeficiency, common variable, 15 PMID:28782633 [Fam.I:III.11(P8)]
101740 M 210300tree icon 9 North American Absent ab-response to pneumococcal polysaccharide vaccine Immunodeficiency, common variable, 15 PMID:28782633 [Fam.I:III.13(P9)]
101741 F 210300tree icon 7 North American Absent ab-response to pneumococcal polysaccharide vaccine Immunodeficiency, common variable, 15 PMID:28782633 [Fam.I:III.14(P10)]
101757 M 210026 11 North American Absent ab-response to pneumococcal polysaccharide vaccine Immunodeficiency, common variable, 8 PMID:26768763 [Fam.605:P14]; PMID:26206937 [P3]
101758 M 210027 10 North American Absent ab-response to pneumococcal polysaccharide vaccine Immunodeficiency, common variable, 8 PMID:26768763 [Fam.606:P15]; PMID:26206937 [P5]
101759 F 210028 12 North American Absent ab-response to pneumococcal polysaccharide vaccine Immunodeficiency, common variable, 8 PMID:26768763 [Fam.607:P16]; PMID:26206937 [P4]
101800 M 215769tree icon - Caucasian Absent ab-response to pneumococcal polysaccharide vaccine NFKB1 insufficiency PMID:34975878 [Fam.F259:P259]; PMID:32278790 [Fam.AT:III.2(III.2)]; PMID:150198 [Fam.BT:IV.1(319)]; PMID:31803180 [Fam.C:III.1(III.1)]
102224 F 214919 - German Absent ab-response to pneumococcal polysaccharide vaccine DiGeorge syndrome PMID:35486341 [P017]
102731 F 214982tree icon 8 Colombian Negative ab-response to vaccination Immunodeficiency 99 PMID:32484799 [Patient(II.2)]
103999 M 215320tree icon - Reduced ab-response to pneumococcal polysaccharide vaccine Infantile-Onset Multisystem Autoimmune Disease 1 PMID:25359994 [P3]
104000 M 215321 - Reduced ab-response to pneumococcal polysaccharide vaccine Infantile-Onset Multisystem Autoimmune Disease 1 PMID:25359994 [P4]
104985 F 215622tree icon - Dutch Negative ab-response to vaccination PMID:32278790 [Fam.NA:IV.3(IV.3)]; PMID:26279205 [Fam.NL1:IV.4(46)]; PMID:11583829 [Fam.1:IV.3(IV:2)]; PMID:16639407 [Fam.1:IV.4(46)]; PMID:150198 [Fam.AA:IV.4(060)]
104989 F 215622tree icon - Dutch Negative ab-response to vaccination NFKB1 insufficiency PMID:32278790 [Fam.NA:IV.7(IV.7)]; PMID:26279205 [Fam.NL1:IV.8(49)]; PMID:29403474 [Fam.NL1 (5):IV.8(49)]; PMID:11583829 [Fam.1:IV.6(IV:6)]; PMID:16639407 [Fam.1:IV.6(49)]; PMID:150198 [Fam.AA:IV.8(064)]
105075 M 215636 - Spanish Reduced ab-response to pneumococcal polysaccharide vaccine Combined immunodeficiency 36 PMID:35464398 [P5(II.1)]
105175 M 215660 - Caucasian Reduced ab-response to pneumococcal polysaccharide vaccine CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.Q:II.1(Q.II.1 (44))]; PMID:27102614 [Fam.B:I.1(2)]
105176 F 215661 - Caucasian Reduced ab-response to pneumococcal polysaccharide vaccine CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.L:II.1(L.II.1 (35))]; PMID:27102614 [Fam.C:II.1(3)]
105179 F 215661 - Caucasian Reduced ab-response to pneumococcal polysaccharide vaccine CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.L:I.2(L.I.2 (34))]; PMID:27102614 [Fam.C:I.2(mother)]
105180 M 215662 - Caucasian Reduced ab-response to pneumococcal polysaccharide vaccine CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.S:II.1(S.II.1 (47))]; PMID:27102614 [Fam.D:II.1(5)]
105197 M 215666tree icon 31 Finnish Reduced ab-response to pneumococcal polysaccharide vaccine NFKB1 insufficiency PMID:32278790 [Fam.F1:III.3(III.3)]; PMID:29403474 [Fam.1 (9):III.3(F1.III-3)]; PMID:28115215 [Fam.1:III.3(F1.III-3)]; PMID:150198 [Fam.AQ:III.3(177)]; PMID:36356849 [Fam.6:III.3(F6:III:3)]; PMID:36105815 [Fam.H67R:III.3(H67R/4)]
105212 F 215666tree icon 50 Finnish Reduced ab-response to pneumococcal polysaccharide vaccine NFKB1 insufficiency PMID:32278790 [Fam.F1:II.4(II.4)]; PMID:29403474 [Fam.1 (9):II.4(F1.II-4)]; PMID:28115215 [Fam.1:II.4(F1.II-4)]; PMID:150198 [Fam.AQ:II.4(174)]; PMID:36356849 [Fam.6:II.4(F6:II:4)]; PMID:36105815 [Fam.H67R:II.4(H67R/2)]
105214 F 215666tree icon 40 Finnish Reduced ab-response to pneumococcal polysaccharide vaccine NFKB1 insufficiency PMID:32278790 [Fam.F1:III.2(III.2)]; PMID:29403474 [Fam.1 (9):III.2(F1.III-2)]; PMID:28115215 [Fam.1:III.2(F1.III-2)]; PMID:150198 [Fam.AQ:III.2(176)]; PMID:36356849 [Fam.6:III.2(F6:III:2)]; PMID:36105815 [Fam.H67R:III.2(H67R/3)]
105218 F 215666tree icon 25 Finnish Reduced ab-response to pneumococcal polysaccharide vaccine NFKB1 insufficiency PMID:32278790 [Fam.F1:III.6(III.6)]; PMID:29403474 [Fam.1 (9):III.6(F1.III-6)]; PMID:28115215 [Fam.1:III.6(F1.III-6)]; PMID:150198 [Fam.AQ:III.6(180)]; PMID:36356849 [Fam.6:III.6(F6:III:6)]; PMID:36105815 [Fam.H67R:III.6(H67R/5)]
105220 F 215666tree icon 15 Finnish Reduced ab-response to pneumococcal polysaccharide vaccine NFKB1 insufficiency PMID:32278790 [Fam.F1:III.8(III.8)]; PMID:29403474 [Fam.1 (9):III.8(F1.III-8)]; PMID:28115215 [Fam.1:III.8(F1.III-8)]; PMID:150198 [Fam.AQ:III.8(182)]; PMID:36356849 [Fam.6:III.8(F6:III:8)]; PMID:36105815 [Fam.H67R:III.8(H67R/7)]
105221 M 215666tree icon 10 Finnish Reduced ab-response to pneumococcal polysaccharide vaccine NFKB1 insufficiency PMID:32278790 [Fam.F1:IV.2(IV.2)]; PMID:28115215 [Fam.1:IV.1(F1.IV-1)]; PMID:150198 [Fam.AQ:IV.1(183)]; PMID:36356849 [Fam.6:IV.1(F6:IV:1)]; PMID:36105815 [Fam.H67R:IV.1(H67R/8)]
105225 F 215671tree icon 57 Finnish Reduced ab-response to pneumococcal polysaccharide vaccine NFKB1 insufficiency PMID:32278790 [Fam.F2:II.2(II.2)]; PMID:29403474 [Fam.2 (9):II.3(F2.II-3)]; PMID:28115215 [Fam.2:II.3(F2.II-3)]; PMID:150198 [Fam.AR:II.3(191)]; PMID:36356849 [Fam.5:II.2(F5:II:2)]
105231 M 215671tree icon 26 Finnish Reduced ab-response to pneumococcal polysaccharide vaccine NFKB1 insufficiency PMID:32278790 [Fam.F2:III.2(III.2)]; PMID:29403474 [Fam.2 (9):III.2(F2.III-2)]; PMID:28115215 [Fam.2:III.2(F2.III-2)]; PMID:150198 [Fam.AR:III.2(193)]; PMID:36356849 [Fam.5:III.2(F5:III:2)]
105363 F 215722 - Afro-American Reduced ab-response to pneumococcal polysaccharide vaccine CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.X:II.1(X.II.1 (59))]; PMID:28366794 [Fam.A:II.1(P1)]
105365 F 215722 - Afro-American Reduced ab-response to pneumococcal polysaccharide vaccine CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.X:I.2(X.I.2 (58))]; PMID:28366794 [Fam.A:I.2(mother)]
105475 F 215776tree icon - European Negative ab-response to vaccination Ezrin immunodeficiency PMID:37301410 [P1(II.4)]
105488 M 215781 - Absent ab-response to pneumococcal polysaccharide vaccine Hyper-IgE recurrent infection syndrome 1 PMID:28983403 [P2]
105587 F 215820 - Caucasian Reduced ab-response to pneumococcal polysaccharide vaccine Activated p110-delta syndrome 1 PMID:24610295 [Fam.1:II.1(F1P1)]
105609 M 215821 - Caucasian Reduced ab-response to pneumococcal polysaccharide vaccine Activated p110-delta syndrome 1 PMID:24610295 [Fam.2:III.1(F2P3)]
105616 F 215822 - Caucasian Reduced ab-response to pneumococcal polysaccharide vaccine Activated p110-delta syndrome 1 PMID:25352054 [Fam.1:II.4(P1)]
105623 M 215822 - Caucasian Reduced ab-response to pneumococcal polysaccharide vaccine Activated p110-delta syndrome 1 PMID:25352054 [Fam.1:II.6(P2)]
105626 M 215822 - Caucasian Reduced ab-response to pneumococcal polysaccharide vaccine Activated p110-delta syndrome 1 PMID:25352054 [Fam.1:III.1(P3)]
105627 F 215822 - Caucasian Reduced ab-response to pneumococcal polysaccharide vaccine Activated p110-delta syndrome 1 PMID:25352054 [Fam.1:III.2(P4)]
105628 F 215822 - Caucasian Reduced ab-response to pneumococcal polysaccharide vaccine Activated p110-delta syndrome 1 PMID:25352054 [Fam.1:III.3(P5)]
105791 F 215877tree icon - Spanish Negative ab-response to vaccination Immunodeficiency, common variable, 14 PMID:37876937 [Fam.1:II.1(1.1)]
105794 M 215878tree icon - Spanish Negative ab-response to vaccination Immunodeficiency, common variable, 14 PMID:37876937 [Fam.2:II.1(2.1)]
105844 M 215889tree icon - Spanish Negative ab-response to vaccination Immunodeficiency, common variable, 14 PMID:37876937 [Fam.4:II.1(4.1)]
105847 M 215890tree icon - Spanish Negative ab-response to vaccination Immunodeficiency, common variable, 14 PMID:37876937 [Fam.5:II.1(5.1)]
105981 M 215919 - Caucasian Reduced ab-response to pneumococcal polysaccharide vaccine CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.Y:II.1(Y.II.1 (61))]
105986 F 215921tree icon - Reduced ab-response to pneumococcal polysaccharide vaccine NFKB1 insufficiency PMID:150198 [Fam.FG:II.2(630)]; PMID:36203612 [Fam.1:II.2(1.II.1)]
105990 F 215921tree icon - Reduced ab-response to pneumococcal polysaccharide vaccine NFKB1 insufficiency PMID:150198 [Fam.FG:III.1(631)]; PMID:36203612 [Fam.1:III.1(1.III.1)]
105991 M 215922tree icon - Reduced ab-response to pneumococcal polysaccharide vaccine NFKB1 insufficiency PMID:150198 [Fam.FH:II.1(634)]; PMID:36203612 [Fam.2:II.2(2.II.1)]
105999 F 215922tree icon - Reduced ab-response to pneumococcal polysaccharide vaccine NFKB1 insufficiency PMID:150198 [Fam.FH:III.1(640)]; PMID:36203612 [Fam.2:III.1(2.III.1)]
106044 F 215929 - Caucasian Reduced ab-response to pneumococcal polysaccharide vaccine CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.KK:II.1(KK.II.1 (85))]
106068 M 215931 - Caucasian Reduced ab-response to pneumococcal polysaccharide vaccine CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.PP:II.1(PP.II.1 (96))]
106069 F 215932 - Caucasian Reduced ab-response to pneumococcal polysaccharide vaccine CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.RR:II.1(RR.II.1 (98))]
106077 M 215934 - Caucasian Reduced ab-response to pneumococcal polysaccharide vaccine CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.TT:II.4(TT.II.4 (103))]
106078 M 215934 - Caucasian Reduced ab-response to pneumococcal polysaccharide vaccine CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.TT:II.5(TT.II.5 (104))]
106097 M 215948 - Caucasian Reduced ab-response to pneumococcal polysaccharide vaccine CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.WW:II.1(WW.II.1 (125))]
106099 M 210955 - Caucasian Reduced ab-response to pneumococcal polysaccharide vaccine CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.ZZ:II.1(ZZ.II.1 (129))]
106200 F 215975tree icon 69 Finnish Reduced ab-response to pneumococcal polysaccharide vaccine NFKB1 insufficiency PMID:150198 [Fam.FM:III.2(693)]; PMID:36356849 [Fam.2:III.2(F2:III:2)]
106209 F 215975tree icon 71 Finnish Reduced ab-response to pneumococcal polysaccharide vaccine NFKB1 insufficiency PMID:150198 [Fam.FM:III.3(694)]; PMID:36356849 [Fam.2:III.3(F2:III:3)]
106216 F 215975tree icon 41 Finnish Reduced ab-response to pneumococcal polysaccharide vaccine NFKB1 insufficiency PMID:150198 [Fam.FM:IV.2(701)]; PMID:36356849 [Fam.2:IV.2(F2:IV:2)]
106223 M 215976tree icon - Finnish Reduced ab-response to pneumococcal polysaccharide vaccine NFKB1 insufficiency PMID:150198 [Fam.FN:II.1(710)]; PMID:36356849 [Fam.4:II.1(F4:II:1)]; PMID:38593810 [Fam.3:II.1(F3.II-1)]
106248 F 215977 - Caucasian Reduced ab-response to pneumococcal polysaccharide vaccine CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.UU:III.15(UU.III.10 (113))]; PMID:29305966 [Fam.IV.2:III.4(III.5)]
106279 M 215977 - Caucasian Reduced ab-response to pneumococcal polysaccharide vaccine CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.UU:V.2(UU.V.2 (122))]; PMID:29305966 [Fam.IV.2:V.1(V.1)]
106371 M 216004 22 Absent ab-response to pneumococcal polysaccharide vaccine CTLA4 haploinsufficiency with autoimmune infiltration PMID:29375547 [Fam.A:II.1(A.II.1)]; PMID:31396201 [P2(II.1)]
106390 M 216005 - Absent ab-response to pneumococcal polysaccharide vaccine CTLA4 haploinsufficiency with autoimmune infiltration PMID:32996901 [Patient(II.1)]
106393 F 216006tree icon 20 German Absent ab-response to pneumococcal polysaccharide vaccine CTLA4 haploinsufficiency with autoimmune infiltration PMID:36273440 [III.3(III.3)]
106463 F 216023tree icon - Japanese Negative ab-response to vaccination NFKB1 insufficiency PMID:150198 [Fam.FX:II.3(779)]; PMID:38514645 [Fam.1:II.3(proband)]
106646 M 216099 - Absent ab-response to pneumococcal polysaccharide vaccine CTLA4 haploinsufficiency with autoimmune infiltration PMID:34628649 [Patient(III.1)]
106676 F 216106tree icon 68 Dutch Reduced ab-response to pneumococcal polysaccharide vaccine NFKB1 insufficiency PMID:150198 [Fam.ET:I.2(598)]; PMID:36105815 [Fam.G64V:I.2(G64V/1)]
106954 M 216196tree icon - Reduced ab-response to pneumococcal polysaccharide vaccine NFKB1 insufficiency PMID:150198 [Fam.GB:II.2(797)]; PMID:38901617 [Fam.2:II.2(P2)]
107043 M 216282 - Reduced ab-response to pneumococcal polysaccharide vaccine Activated p110-delta syndrome 1 PMID:27444043 [P1]
107044 M 216283 - Reduced ab-response to pneumococcal polysaccharide vaccine Activated p110-delta syndrome 1 PMID:28983403 [P1]
107156 F 216365tree icon 10 Turkish Reduced ab-response to pneumococcal polysaccharide vaccine Hyper-IgE recurrent infection syndrome 2 PMID:39437980 [Fam.B:II.2(Patient 2)]

*Age: age reported at the first known time of manifestation; PMID: PubMed ID; GRID: GenIA reference ID (ref. not in PubMed).