Global developmental delay

Basic details

Preferred term: Global developmental delay
Alt. terms: Cognitive delay | Delayed cognitive development | Delayed development | Delayed developmental milestones | Delayed intellectual development | Delayed milestones | Delayed psychomotor development | Developmental delay | Developmental delay in early ch

HPO term: Global developmental delay
HPO code: HP:0001263

GenIA ID: 1779
Last updated on: 2021-08-02 21:50:33

Cross ref. with other ontologies

NCIT: -
MESH: -
EFO: -
OAE: -
SNOMEDCT: -
ICD10: -

Description

A delay in the achievement of motor or mental milestones in the domains of development of a child, including motor skills, speech and language, cognitive skills, and social and emotional skills. This term should only be used to describe children younger than five years of age. Note: Developmental retardation is any significant lag in development in the any or all of the physical, cognitive, behavioral, emotional, or social spheres. Note that the term intellectual disability (mental retardation) refers to not merely a delay in development but rather a permanent limitation. Note that the term 'psychomotor retardation' is also used in some contexts to refer to a slowing of thought and physical movements as a result of major depression or intoxication.

Hierarchical classification

Reported patients added to GenIA DB

SubjectID Sex Fam.ID Age* Population MatchedTerm Diagnosis Reference & Pub.codes
102313 M 214935tree icon - Turkish Neurodevelopmental delay Otofaciocervical syndrome 2 PMID:23851939 [V-2(V.2)]
102353 M 214936tree icon - Indian Neurodevelopmental delay Otofaciocervical syndrome 2 PMID:29681087 [P1(II.1)]
102356 F 214936tree icon - Indian Neurodevelopmental delay Otofaciocervical syndrome 2 PMID:29681087 [Fam.P1:II.2(P2)]
102410 F 214947tree icon 2 South Asian Global developmental delay Hyper-IgE recurrent infection syndrome 4B PMID:28747427 [Fam.A:II.3(P1)]
102419 M 214948tree icon - Irish Traveller Global developmental delay Immunodeficiency 54 PMID:16532402 [Fam.A:IV.8(P1)]; PMID:22354167 [Fam.A:IV.8(P1.1)]
102433 M 214951tree icon - Irish Traveller Global developmental delay Immunodeficiency 54 PMID:22354167 [Fam.B:II.1(P2.1)]
102509 M 214948tree icon - Irish Traveller Global developmental delay Immunodeficiency 54 PMID:16532402 [Fam.A:IV.12(P3)]; PMID:22354167 [Fam.A:IV.12(P1.3)]
102511 M 214948tree icon - Irish Traveller Global developmental delay Immunodeficiency 54 PMID:16532402 [Fam.A:IV.14(P4)]; PMID:22354167 [Fam.A:IV.14(P1.4)]
102512 F 214948tree icon - Irish Traveller Global developmental delay Immunodeficiency 54 PMID:16532402 [Fam.A:IV.15]; PMID:22354167 [Fam.A:IV.15(P1.5)]
102677 M 214980tree icon 3 Pakistani Global developmental delay JAK1 deficiency PMID:28008925 [Patient(II.4)]
102739 F 214984tree icon - Japanese Moderate global developmental delay Autoinflammation, immune dysregulation, and eosinophilia PMID:35046931 [Patient(II.1)]
103076 F 215099tree icon - Omani Global developmental delay Seizures, cortical blindness, microcephaly syndrome PMID:33662367 [Fam.F5:V.5(P6)]
103132 M 215102tree icon - Emirati Global developmental delay Seizures, cortical blindness, microcephaly syndrome PMID:26463574 [Fam.MC36500:IV.6(IV.3)]
103152 F 215104tree icon 0 Omani Global developmental delay Seizures, cortical blindness, microcephaly syndrome PMID:26463574 [Fam.MC2500:IV.9(MC2501)]
103170 F 215104tree icon 0 Omani Global developmental delay PMID:26463574 [Fam.MC2500:IV.10]
103171 M 215104tree icon 2 Omani Global developmental delay Seizures, cortical blindness, microcephaly syndrome PMID:26463574 [Fam.MC2500:IV.11]
104005 F 215326tree icon - Global developmental delay Infantile-Onset Multisystem Autoimmune Disease 1 PMID:25359994 [Fam.1:II.1(P9)]; PMID:35677041 [Pt4]
104402 M 215523tree icon 2 Turkish Neurodevelopmental delay Immunodeficiency 114 PMID:36517554 [Fam.Pt1:IV.4(Pt2)]
104414 M 215526tree icon 8 Turkish Mild global developmental delay Early-onset atopic inflammation PMID:36758835 [Patient(V.3)]
104554 M 215551tree icon - Pakistani Mild global developmental delay Autoinflammation, panniculitis, and dermatosis syndrome PMID:27523608 [Fam.1:V.2(V:2)]; PMID:27559085 [Fam.1:V.2(P1)]; PMID:35587511 [Fam.G:II.2(4)]; PMID:34797715 [P1]; PMID:38914362 [Fam.A:V.2(023)]
104570 F 215551tree icon - Pakistani Global developmental delay Autoinflammation, panniculitis, and dermatosis syndrome PMID:27523608 [Fam.1:IV.4(IV:4)]; PMID:27559085 [Fam.1:IV.3(NA)]; PMID:38914362 [Fam.A:V.7(028)]
104580 F 215553tree icon - Turkish Global developmental delay Autoinflammation, panniculitis, and dermatosis syndrome PMID:27559085 [Fam.3:II.1(P3)]; PMID:35587511 [Fam.H:II.1(3)]; PMID:34797715 [P3]; PMID:38914362 [Fam.C:II.1(039)]
104625 M 215559tree icon - Global developmental delay X-linked multisystem autoinflammatory disease with immune dysregulation PMID:37342957 [Fam.B:II.2(P2)]
104678 F 215569tree icon - Iranian Neurodevelopmental delay Severe early onset systemic inflammation and autoimmunity PMID:37349293 [Fam.2:II.2(P2)]
105261 F 215680 - Egyptian Neurodevelopmental delay Otofaciocervical syndrome 2 PMID:37924468 [Patient(III.1)]
105797 M 215879 - Global developmental delay Infantile-Onset Multisystem Autoimmune Disease 1 PMID:33864888 [S041]
106084 F 215940 - Global developmental delay 4q24 deletion syndrome PMID:150198 [Fam.EN:591]; PMID:35784294 [303816]
106086 M 215942 - Global developmental delay 4q24 deletion syndrome PMID:150198 [Fam.EP:593]; PMID:35784294 [384471]
106246 F 215977 - Caucasian Global developmental delay CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.UU:III.11(UU.III.7 (111))]; PMID:29305966 [Fam.IV.2:III.2(III.2)]
106248 F 215977 - Caucasian Global developmental delay CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.UU:III.15(UU.III.10 (113))]; PMID:29305966 [Fam.IV.2:III.4(III.5)]
106250 M 215977 - Caucasian Global developmental delay CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.UU:III.5(UU.III.4 (109))]; PMID:29305966 [Fam.IV.2:III.6(III.8)]
106281 M 215977 - Caucasian Global developmental delay CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.UU:V.1(UU.V.1 (121))]; PMID:29305966 [Fam.IV.2:V.3(V.3)]
106448 F 216016tree icon - Japanese Neurodevelopmental delay Autoinflammation, panniculitis, and dermatosis syndrome 2 PMID:38914362 [Fam.R:II.1(130)]; PMID:38652464 [Fam.1:II.1(Patient)]
106654 M 216101tree icon 0 Syrian Global developmental delay Intellectual disability due to EZR deficiency PMID:25504542 [Fam.MR037:IV.1(IV-1)]
106667 M 216101tree icon 0 Syrian Global developmental delay Intellectual disability due to EZR deficiency PMID:25504542 [Fam.MR037:IV.3(IV-3)]
107161 F 216366tree icon - Sri Lankan Tamil Global developmental delay Adenosine deaminase 2 deficiency PMID:26607704 [P1(II.1)]
107212 F 216374 1,- Arab Global developmental delay,Neurodevelopmental delay Combined immunodeficiency 37 PMID:31775018 [Patient]

*Age: age reported at the first known time of manifestation; PMID: PubMed ID; GRID: GenIA reference ID (ref. not in PubMed).