Increased IgM levels

Basic details

Preferred term: Increased IgM levels
Alt. terms: Increased levels of IgM | Increased circulating IgM level

HPO term: Increased circulating IgM level
HPO code: HP:0003496

GenIA ID: 23
Last updated on: 2021-12-10 17:55:48

Cross ref. with other ontologies

NCIT: -
MESH: -
EFO: -
OAE: -
SNOMEDCT: -
ICD10: -

Description

An abnormally increased level of immunoglobulin M in blood.

Hierarchical classification

Reported patients added to GenIA DB

SubjectID Sex Fam.ID Age* Population MatchedTerm Diagnosis Reference & Pub.codes
101028 F 210750 42 German Increased IgM levels PMID:34975878 [Fam.F013:P013]
101043 M 210725tree icon 20 Caucasian Increased IgM levels CTLA4 haploinsufficiency with autoimmune infiltration PMID:29729943 [Fam.H:II.2(30)]; PMID:34975878 [Fam.F017:P017]
101104 F 211429 5 Increased IgM levels Activated p110-delta syndrome 1 PMID:34975878 [Fam.F397:P397]
101139 F 212090 25 Increased IgM levels PMID:34975878 [Fam.F399:P399]
101444 F 210640 35 Increased IgM levels PMID:34975878 [Fam.F145:P145]
101501 F 212459 - British Increased IgM levels Activated p110-delta syndrome 1 PMID:24136356 [Fam.A:II.2(P4)]
101509 F 212459 - British Increased IgM levels Activated p110-delta syndrome 1 PMID:24136356 [Fam.A:III.2(P1)]
101511 M 212459 - British Increased IgM levels Activated p110-delta syndrome 1 PMID:24136356 [Fam.A:III.3(P2)]
101512 M 212459 - British Increased IgM levels Activated p110-delta syndrome 1 PMID:24136356 [Fam.A:III.4(P3)]
101530 M 212460 - British Increased IgM levels Activated p110-delta syndrome 1 PMID:24136356 [Fam.B:III.3(P5)]
101532 F 212460 - British Increased IgM levels Activated p110-delta syndrome 1 PMID:24136356 [Fam.B:III.5(P6)]
101534 M 212460 - British Increased IgM levels Activated p110-delta syndrome 1 PMID:24136356 [Fam.B:IV.1(P11)]
101541 M 212461 - Slovenian Increased IgM levels Activated p110-delta syndrome 1 PMID:24136356 [Fam.C:II.1(P8)]
101546 F 212462 - Irish Increased IgM levels Activated p110-delta syndrome 1 PMID:24136356 [Fam.D:II.1(P10)]
101548 M 212462 - Irish Increased IgM levels Activated p110-delta syndrome 1 PMID:24136356 [Fam.D:III.1(P9)]
101549 F 212463 - British Increased IgM levels Activated p110-delta syndrome 1 PMID:24136356 [Fam.E:I.1(P13)]
101552 M 212464 - French Increased IgM levels Activated p110-delta syndrome 1 PMID:24136356 [Fam.F:II.1(P14)]
101560 M 212465 - French Increased IgM levels Activated p110-delta syndrome 1 PMID:24136356 [Fam.G:II.2(P15)]
101561 F 212465 - French Increased IgM levels Activated p110-delta syndrome 1 PMID:24136356 [Fam.G:II.3(P16)]
101578 M 210205tree icon 33 German Increased IgM levels CTLA4 haploinsufficiency with autoimmune infiltration PMID:25329329 [Fam.A:II.14(A.II.8)]; PMID:29729943 [Fam.A:II.14(A.II.8 (5))]; PMID:27418640 [P8(5)]
101596 M 212618tree icon 4 Jewish Increased IgM levels ARPC1B deficiency PMID:29127144 [P1(II.1)]
101687 F 212635tree icon 1 Nepalese Increased IgM levels ARPC1B deficiency PMID:30771411 [P12(II.1)]
102216 F 214916tree icon 3 Belgian Hypergammaglobulinaemia Severe congenital neutropenia 11 PMID:32325141 [Patient(II.1)]
102260 F 214926tree icon - Mexican Increased IgM levels ARPC1B deficiency PMID:32683750 [Fam.case:II.2(sister)]; PMID:36708766 [Fam.A:II.2(P1)]
102410 F 214947tree icon 1 South Asian Increased IgM levels Hyper-IgE recurrent infection syndrome 4B PMID:28747427 [Fam.A:II.3(P1)]
102901 F 215008tree icon 0 Brasilian Hypergammaglobulinaemia T-cell immunodeficiency, congenital alopecia, and nail dystrophy PMID:35064468 [patient(II.2)]
103547 M 215157tree icon 11 Mexican Increased IgM levels ARPC1B deficiency PMID:36708766 [Fam.D:II.4(P6)]
104001 F 215322tree icon - North American Increased IgM levels Infantile-Onset Multisystem Autoimmune Disease 1 PMID:25359994 [P5]; PMID:32392079 [P3]; PMID:30092289 [P15]; PMID:35677041 [Pt3]; PMID:33651637 [Patient 1]
104540 M 215549tree icon -,- North African Hypergammaglobulinaemia,Increased IgM levels X-linked multisystem autoinflammatory disease with immune dysregulation PMID:36952639 [Fam.F:II.1(Patient F)]
104554 M 215551tree icon 3 Pakistani Increased IgM levels Autoinflammation, panniculitis, and dermatosis syndrome PMID:27523608 [Fam.1:V.2(V:2)]; PMID:27559085 [Fam.1:V.2(P1)]; PMID:35587511 [Fam.G:II.2(4)]; PMID:34797715 [P1]; PMID:38914362 [Fam.A:V.2(023)]
104568 F 215551tree icon 0 Pakistani Increased IgM levels Autoinflammation, panniculitis, and dermatosis syndrome PMID:27523608 [Fam.1:IV.3(IV:3)]; PMID:32231246 [IV:3(IV.3)]; PMID:27559085 [Fam.1:IV.1(P4)]; PMID:38914362 [Fam.A:V.6(027)]
104846 F 215580 0 Egyptian Increased IgM levels Omenn syndrome 2 PMID:30307608 [1]
105045 M 215631tree icon 24 Caucasian Increased IgM levels CTLA4 haploinsufficiency with autoimmune infiltration PMID:27379089 [P10]
105093 F 215639tree icon 19 Israeli Increased IgM levels NFKB1 insufficiency PMID:32278790 [Fam.AA:II.2(II.2)]; PMID:29403474 [Patient 2 (8)]; PMID:27365489 [Fam.2:II.2(Pat.2)]; PMID:150198 [Fam.AF:II.2(127)]
105350 M 215712 2 Omani Hypergammaglobulinaemia Immunodeficiency, common variable, 8 PMID:28690850 [P1]
105481 M 215777tree icon - Haitian/Hispanic Increased IgM levels Activated p110-delta syndrome 1 PMID:24165795 [Fam.A:II.1(A.1)]
105482 F 215778tree icon - Caucasian Increased IgM levels Activated p110-delta syndrome 1 PMID:24165795 [Fam.B:I.2(I.2)]
105484 F 215778tree icon - Caucasian Increased IgM levels Activated p110-delta syndrome 1 PMID:24165795 [Fam.B:III.1(B.III.1)]
105487 F 215780tree icon - Afro-American Increased IgM levels Activated p110-delta syndrome 1 PMID:24165795 [Fam.G:II.1(G.1)]
105537 M 215793 - Increased IgM levels Activated p110-delta syndrome 1 PMID:24698326 [P1]
105587 F 215820 - Caucasian Increased IgM levels Activated p110-delta syndrome 1 PMID:24610295 [Fam.1:II.1(F1P1)]
105591 F 215821 - Caucasian Increased IgM levels Activated p110-delta syndrome 1 PMID:24610295 [Fam.2:II.1(F2P2)]
105607 F 215821 - Caucasian Increased IgM levels PMID:24610295 [Fam.2:II.3]
105609 M 215821 - Caucasian Increased IgM levels Activated p110-delta syndrome 1 PMID:24610295 [Fam.2:III.1(F2P3)]
105617 F 215822 - Caucasian Increased IgM levels PMID:25352054 [Fam.1:I.1(I.1)]
105626 M 215822 - Caucasian Increased IgM levels Activated p110-delta syndrome 1 PMID:25352054 [Fam.1:III.1(P3)]
105627 F 215822 3 Caucasian Increased IgM levels Activated p110-delta syndrome 1 PMID:25352054 [Fam.1:III.2(P4)]
105628 F 215822 - Caucasian Increased IgM levels Activated p110-delta syndrome 1 PMID:25352054 [Fam.1:III.3(P5)]
105635 F 215829 - Caucasian Increased IgM levels Activated p110-delta syndrome 1 PMID:26371693 [1]
105657 F 215835 - Increased IgM levels Activated p110-delta syndrome 1 PMID:27379089 [11]
106352 M 215998tree icon 3 Increased IgM levels Activated p110-d syndrome 2 PMID:34922003 [Fam.B:II.1(B1)]
106463 F 216023tree icon - Japanese Hypergammaglobulinaemia NFKB1 insufficiency PMID:150198 [Fam.FX:II.3(779)]; PMID:38514645 [Fam.1:II.3(proband)]
106642 F 216097 2 European Hypergammaglobulinaemia CTLA4 haploinsufficiency with autoimmune infiltration PMID:31396201 [Fam.:II.1(P1)]
106888 M 216182tree icon 10 Caucasian Hypergammaglobulinaemia Adenosine deaminase 2 deficiency PMID:28830446 [P1(II.1)]
106889 M 216182tree icon 4 Caucasian Hypergammaglobulinaemia Adenosine deaminase 2 deficiency PMID:28830446 [Fam.P1:II.2(P2)]
106932 M 216188tree icon 5 Jewish Hypergammaglobulinaemia Adenosine deaminase 2 deficiency PMID:25075848 [patient]; PMID:30139808 [Fam.1:II.5(P)]
107176 M 216369 - Hypergammaglobulinaemia T-cell LGL leukemia 1 PMID:26419508 [Patient 1]
107226 M 216382 13 North American Increased IgM levels Infantile-Onset Multisystem Autoimmune Disease 1 PMID:35677041 [Pt6]; PMID:33651637 [Patient 2]; PMID:28349047 [Case]

*Age: age reported at the first known time of manifestation; PMID: PubMed ID; GRID: GenIA reference ID (ref. not in PubMed).