Hemophagocytosis
Basic details
Preferred term: Hemophagocytosis
Alt. terms:
HPO term: Hemophagocytosis
HPO code: HP:0012156
GenIA ID: 9046
Last updated on: 2021-08-02 21:50:33
Cross ref. with other ontologies
NCIT: -
MESH: -
EFO: -
OAE: -
SNOMEDCT: -
ICD10: -
Description
Phagocytosis by macrophages of erythrocytes, leukocytes, platelets, and their precursors in bone marrow and other tissues. Note: Hemophagocytosis is a nonspecific phenotypic feature observed in several conditions including hemolytic anemia, malignant disease, infections, and hemophagocytic syndrome (also known as hemophagocytic lymphohistiocytosis, a rare hyperinflammatory syndrome caused by severe hypercytokinemia due to a highly stimulated but ineffective immune process).
Hierarchical classification
PARENT terms
TERM
Hemophagocytosis
Reported patients added to GenIA DB
SubjectID | Sex | Fam.ID | Age* | Population | MatchedTerm | Diagnosis | Reference & Pub.codes |
---|---|---|---|---|---|---|---|
102626 | M | 214969![]() |
- | Filipino | Hemophagocytosis | Immunodeficiency 98 with autoinflammation, somatic | PMID:33512449 [Fam.1:II.1(P1)] |
102987 | F | 215075![]() |
14 | Austrian | Hemophagocytosis | Immunodeficiency 97 | PMID:33054089 [Patient(II.1)] |
103454 | M | 215130![]() |
7 | Saudi | Hemophagocytosis | infantile-onset multisystem autoimmune disease-3 | PMID:36006710 [Fam.2:II.2(P2)] |
103485 | F | 215137![]() |
10 | French | Hemophagocytosis | Immunodeficiency 55 | PMID:28414293 [Fam.D:II.1(P5)] |
105103 | F | 215641 | 11 | South Korean | Hemophagocytosis | CTLA4 haploinsufficiency with autoimmune infiltration | PMID:26478010 [III.2(III.2)] |
*Age: age reported at the first known time of manifestation; PMID: PubMed ID; GRID: GenIA reference ID (ref. not in PubMed).