Information on CANDF8
Basic details
Name: Candidiasis, familial 8 | Acronym: CANDF8
Alt. names:
Gene: TRAF3IP2 | MOI: Autosomal recessive | Mechanism of action:
No. of cases in DB: 0 | First reported in: 2013
Last updated on: 2023-02-28 16:41:18 by
Description
Individuals have been reported as having recurrent candidal (and other) infections, and surveillance, prophylaxis, and early treatment may be beneficial. Refs. PMIDs: 24120361
Management
Description of management option has not been reviewed yet.
Please mind that full curation of this condition has not started yet. Please contact us if you want to volunteer.
0 reported cases added to GenIA
| SubjectID | Sex | Fam.ID | AD | AFM | Validity | Country | Population | Reference & Pub.code |
|---|
AD: Age at genetic diagnosis; AFM: age at first manifestation; PMID: PubMed ID; GRID: GenIA reference ID (ref. not in PubMed).
Summary of clinical findings
[Considering only Definitive and Possible cases]
| Rank | Clinical term | Present | Absent | Unreported |
|---|---|---|---|---|
| 1 | Oral candidiasis |
2 (99.9%) | 0 (0.0%) | 0 (0.0%) |
| 2 | Seborrheic dermatitis |
2 (99.9%) | 0 (0.0%) | 0 (0.0%) |
| 3 | Blepharitis |
1 (50.0%) | 0 (0.0%) | 1 (50.0%) |
| 4 | Cheilitis |
1 (50.0%) | 0 (0.0%) | 1 (50.0%) |
| 5 | Childhood onset |
1 (50.0%) | 0 (0.0%) | 1 (50.0%) |
| 6 | Juvenile onset |
1 (50.0%) | 0 (0.0%) | 1 (50.0%) |
| 7 | Macroglossia |
1 (50.0%) | 0 (0.0%) | 1 (50.0%) |
| 8 | Onychomycosis |
1 (50.0%) | 0 (0.0%) | 1 (50.0%) |
Please mind that full curation of this condition has not started yet. Please contact us if you want to volunteer.
Summary of treatment outcomes
[Considering only Definitive and Possible cases]
| Treatment ⓘ | Responses & clinical indications |
|---|
Please mind that full curation of this condition has not started yet. Please contact us if you want to volunteer.