Information on RALD2
Basic details
Name: RAS-associated autoimmune lymphoproliferative syndrome type IV | Acronym: RALD2
Alt. names:
Gene: NRAS | MOI: Somatic | Mechanism of action: Gain of Function
No. of cases in DB: 0 | First reported in: 2007
Last updated on: 2023-02-28 16:41:18 by
Description
The condition may also include cardiac anomalies and dysrhythmias, and appropriate care may be beneficial; Individuals with Autoimmune lymphoproliferative syndrome type IV may be at risk of hematologic malignancies, and individuals with Noonan syndrome 6 have been described with juvenile myelomonocytic leukemia such that surveillance/early treatment may reduce morbidity. Noonan syndrome may include multiple congenital anomalies. Refs. PMIDs: 17517660; 19775298; 19966803; 20301303; 21901340; 22855653; 22887781
Management
Description of management option has not been reviewed yet.
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0 reported cases added to GenIA
| SubjectID | Sex | Fam.ID | AD | AFM | Validity | Country | Population | Reference & Pub.code |
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AD: Age at genetic diagnosis; AFM: age at first manifestation; PMID: PubMed ID; GRID: GenIA reference ID (ref. not in PubMed).
Summary of clinical findings
[Considering only Definitive and Possible cases]
| Rank | Clinical term | Present | Absent | Unreported |
|---|
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Summary of treatment outcomes
[Considering only Definitive and Possible cases]
| Treatment ⓘ | Responses & clinical indications |
|---|
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