Information on IIAE7
Basic details
Name: Susceptibility to acute infection-induced encephalopathy type 7 | Acronym: IIAE7
Alt. names: {Encephalopathy, acute, infection-induced, 7, susceptibility to}
Gene: IRF3 | MOI: Autosomal dominant | Mechanism of action:
No. of cases in DB: 0 | First reported in: 2015
Last updated on: 2023-02-28 16:41:18 by
Description
Individuals may be susceptible to severe herpes simplex virus infections includingherpes encephalitis has been described, and awareness may allow early diagnosis and treatment, potentially decreasing morbidity and mortality. Refs. PMIDs: 26216125
Management
Description of management option has not been reviewed yet.
Please mind that full curation of this condition has not started yet. Please contact us if you want to volunteer.
0 reported cases added to GenIA
| SubjectID | Sex | Fam.ID | AD | AFM | Validity | Country | Population | Reference & Pub.code |
|---|
AD: Age at genetic diagnosis; AFM: age at first manifestation; PMID: PubMed ID; GRID: GenIA reference ID (ref. not in PubMed).
Summary of clinical findings
[Considering only Definitive and Possible cases]
| Rank | Clinical term | Present | Absent | Unreported |
|---|---|---|---|---|
| 1 | CSF lymphocytic pleiocytosis |
1 (99.9%) | 0 (0.0%) | 0 (0.0%) |
| 2 | Headaches |
1 (50.0%) | 0 (0.0%) | 1 (50.0%) |
| 3 | Herpes simplex encephalitis |
1 (50.0%) | 0 (0.0%) | 1 (50.0%) |
| 4 | Juvenile onset |
1 (99.9%) | 0 (0.0%) | 0 (0.0%) |
| 5 | Nuchal rigidity |
1 (50.0%) | 0 (0.0%) | 1 (50.0%) |
| 6 | Seizures |
1 (50.0%) | 0 (0.0%) | 1 (50.0%) |
Please mind that full curation of this condition has not started yet. Please contact us if you want to volunteer.
Summary of treatment outcomes
[Considering only Definitive and Possible cases]
| Treatment ⓘ | Responses & clinical indications |
|---|
Please mind that full curation of this condition has not started yet. Please contact us if you want to volunteer.