Information on subject 101015

Basic details

Sex: Male

Country: Germany

Population: German

Family ID: 210203

Father:

Mother:

Consanguinity: Unknown

Clin. status: Affected

Age of death:

Ref.ID & pub.codes

2018 [112] Fam.MM:II.1(87)
2018 [109] MM.II.1
2019 [1013] Patient 3
2021 [118] Fam.F002:P002
2022 [1271] AM.II.1 (87)

Genetic conditions

Code	Condition's_name	MOI [ℹ]	AD/AS	AFM	Validity [ℹ]
CHAI	CTLA4 haploinsufficiency with autoimmune infiltration	AD	38.00	14.00	Definitive

Genetic variants

Gene	Var.name ⓘ	Exon/Intron	CDS_change	Prot.change	Var.type	Var.class	Zygosity	Relevant
TNFRSF13B	R72H	EX3	c.215G>A	p.Arg72His	missense_variant	Uncertain significance	HET	Uncertain
CTLA4	F179Cfs*29	EX3	c.531_544del	p.Phe179CysfsTer29	frameshift_variant	Pathogenic	HET	Yes, alone
CTLA4	-318C>T	5'UTR	c.-318C>T		upstream_gene_variant	Risk allele	WT	No
TICAM1	S160F	EX2	c.479C>T	p.Ser160Phe	missense_variant	Risk allele	HET	Unassigned

Clinical manifestations

Age	Sign/Symptom	Present?	Severity	Presentation
22.68	Diarrhea	Yes		chronic
17.68	Decreased IgA levels	Yes	severe
17.68	Decreased IgG levels	Yes
13.68	Recurrent lower respiratory tract infections	Yes		recurrent
13.68	Recurrent upper respiratory tract infection	Yes		recurrent
13.68	(unusual) Respiratory tract infection	Yes		recurrent
17.68	Decreased IgM levels	Yes	mild
31.60	Splenomegaly	Yes		chronic
32.83	Splenomegaly	Yes
Unk.	Abnormal lymphoproliferation	Yes
13.69	Autoimmune hemolytic anemia	Yes
17.35	Autoimmune thrombocytopenia	Yes		acute
18.77	Autoimmune thrombocytopenia	Yes		acute
33.01	Autoimmune thrombocytopenia	Yes		acute
40.84	Lung disease	Yes		chronic
22.68	Enteropathy	Yes		chronic
32.21	Allergy	Yes
26.00	Urticaria	Yes
40.60	Urticaria	Yes		recurrent
25.68	Intestinal lymphoid nodular hyperplasia	Yes
32.83	Crohn ileitis	Yes
32.83	Restrictive ventilatory defect	Yes
40.84	Restrictive ventilatory defect	Yes		chronic
32.83	Chronic CSF lymphocytosis	Yes
32.83	Migraine	Yes
36.18	Migraine	Yes		chronic
20.00	Urinary incontinence	Yes
33.00	Hodgkin lymphoma	Yes
23.00	Enteritis	Yes
25.68	Enteritis	Yes		chronic
19.68	Encephalitis	Yes		recurrent
13.68	Pneumonia	Yes		recurrent
19.68	Granulomatosis	Yes		recurrent
38.68	Gastritis	Yes	mild	acute
13.68	Sinusitis	Yes		chronic
33.36	Sinusitis	Yes		chronic
22.68	Gastrointestinal inflammation	Yes		recurrent
41.45	Hepatic steatosis	No
17.35	Thrombocytopenia	Yes		acute
18.77	Thrombocytopenia	Yes		acute
31.60	Lymphadenopathy	No
33.00	Lymphadenopathy	Yes
40.60	Severe Norovirus infection	No
40.60	Osteoporosis	Yes		chronic
30.76	Antinuclear antibodies	No
30.76	Antiphospholipid antibody positive	No
27.63	Rheumatoid factor positive	No
33.01	Neoplasm	Yes
Unk.	Nervous system abnormality	Yes
40.60	Anemia	Yes
Unk.	Herpes Simplex Virus Infection	Yes
26.00	Lymphoid nodular hyperplasia of colon	Yes
33.82	Drug-induced osteoporosis	Yes		chronic
Unk.	(unusual) Epstein-Barr virus infection	Yes
41.45	Hepatic fibrosis	No
Unk.	Crohn's disease	Yes
36.68	Varicella zoster virus infection	Yes		acute
40.60	Rotavirus infection	No
25.68	Ileitis	Yes		chronic
Unk.	Brain lymphocytic infiltration	Yes
Unk.	Persistent EBV viremia	Yes
33.00	Triggered by EBV infection	Yes
Unk.	Absent ab-response to pneumococcal polysaccharide vaccine	Yes
14.00	Common variable immunodeficiency	Yes
Unk.	Anti-CMV antibody positivity	No

Cell counts

Age	Cell_type	Cells/ul	Ref.range	Relative(%)	Ref.range(%)	Result
19.75	Leukocytes	11000	4000 - 13000			Normal
19.75	Platelets	183000	150000 - 400000			Normal
21.56	Platelets	238000	150000 - 400000			Normal
21.56	Basophils			0.00	0.00 - 2.00	Normal
21.56	Lymphocytes			8.00	19.00 - 51.00	Low
21.56	Leukocytes	6600	4000 - 13000			Normal
21.63	Lymphocytes			13.00	19.00 - 51.00	Low
21.63	Leukocytes	6200	4000 - 13000			Normal
21.63	Platelets	247000	150000 - 400000			Normal
21.63	Basophils			0.00	0.00 - 2.00	Normal
21.71	Platelets	224000	150000 - 400000			Normal
21.71	Basophils			0.00	0.00 - 2.00	Normal
21.71	Lymphocytes			12.00	19.00 - 51.00	Low
21.71	Leukocytes	7000	4000 - 13000			Normal
21.79	Lymphocytes			5.00	19.00 - 51.00	Low
21.79	Leukocytes	9000	4000 - 13000			Normal
21.79	Platelets	262000	150000 - 400000			Normal
21.79	Basophils			2.00	0.00 - 2.00	Normal
21.87	Basophils			2.00	0.00 - 2.00	Normal
21.87	Lymphocytes			16.00	19.00 - 51.00	Low
21.87	Leukocytes	4500	4000 - 13000			Normal
21.87	Platelets	167000	150000 - 400000			Normal
21.94	Lymphocytes			10.00	19.00 - 51.00	Low
21.94	Leukocytes	6300	4000 - 13000			Normal
21.94	Platelets	236000	150000 - 400000			Normal
21.94	Basophils			2.00	0.00 - 2.00	Normal
22.02	Lymphocytes			10.00	19.00 - 51.00	Low
22.02	Leukocytes	7600	4000 - 13000			Normal
22.02	Platelets	217000	150000 - 400000			Normal
22.02	Basophils			1.00	0.00 - 2.00	Normal
22.09	Platelets	202000	150000 - 400000			Normal
22.09	Basophils			0.00	0.00 - 2.00	Normal
22.09	Lymphocytes			19.00	19.00 - 51.00	Normal
22.09	Leukocytes	4500	4000 - 13000			Normal
22.18	Lymphocytes			10.00	19.00 - 51.00	Low
22.18	Leukocytes	4600	4000 - 13000			Normal
22.18	Platelets	194000	150000 - 400000			Normal
22.18	Basophils			1.00	0.00 - 2.00	Normal
22.25	Platelets	209000	150000 - 400000			Normal
22.25	Basophils			0.00	0.00 - 2.00	Normal
22.25	Lymphocytes			28.00	19.00 - 51.00	Normal
22.25	Leukocytes	4800	4000 - 13000			Normal
22.32	Lymphocytes			19.00	19.00 - 51.00	Normal
22.32	Leukocytes	3900	4000 - 13000			Low
22.32	Platelets	183000	150000 - 400000			Normal
22.32	Basophils			0.00	0.00 - 2.00	Normal
22.40	Basophils			1.00	0.00 - 2.00	Normal
22.40	Lymphocytes			16.00	19.00 - 51.00	Low
22.40	Leukocytes	5200	4000 - 13000			Normal
22.40	Platelets	177000	150000 - 400000			Normal
22.48	Lymphocytes			24.00	19.00 - 51.00	Normal
22.48	Leukocytes	5100	4000 - 13000			Normal
22.48	Platelets	187000	150000 - 400000			Normal
22.48	Basophils			1.00	0.00 - 2.00	Normal
22.55	Lymphocytes			18.00	19.00 - 51.00	Low
22.55	Leukocytes	4700	4000 - 13000			Normal
22.55	Platelets	203000	150000 - 400000			Normal
22.55	Basophils			0.00	0.00 - 2.00	Normal
22.63	Platelets	177000	150000 - 400000			Normal
22.63	Basophils			1.00	0.00 - 2.00	Normal
22.63	Lymphocytes			11.00	19.00 - 51.00	Low
22.63	Leukocytes	3700	4000 - 13000			Low
22.71	Lymphocytes			11.00	19.00 - 51.00	Low
22.71	Leukocytes	5300	4000 - 13000			Normal
22.71	Platelets	196000	150000 - 400000			Normal
22.71	Basophils			0.00	0.00 - 2.00	Normal
22.78	Platelets	217000	150000 - 400000			Normal
22.78	Basophils			0.00	0.00 - 2.00	Normal
22.78	Lymphocytes			24.00	19.00 - 51.00	Normal
22.78	Leukocytes	6900	4000 - 13000			Normal
22.86	Lymphocytes			22.00	19.00 - 51.00	Normal
22.86	Leukocytes	5700	4000 - 13000			Normal
22.86	Platelets	238000	150000 - 400000			Normal
22.86	Basophils			1.00	0.00 - 2.00	Normal
22.94	Platelets	201000	150000 - 400000			Normal
22.94	Basophils			0.00	0.00 - 2.00	Normal
22.94	Lymphocytes			14.00	19.00 - 51.00	Low
22.94	Leukocytes	6900	4000 - 13000			Normal
23.01	Lymphocytes			10.00	19.00 - 51.00	Low
23.01	Leukocytes	4300	4000 - 13000			Normal
23.01	Platelets	180000	150000 - 400000			Normal
23.01	Basophils			1.00	0.00 - 2.00	Normal
23.09	Basophils			3.00	0.00 - 2.00	High
23.09	Lymphocytes			15.00	19.00 - 51.00	Low
23.09	Leukocytes	3700	4000 - 13000			Low
23.09	Platelets	190000	150000 - 400000			Normal
23.17	Lymphocytes			20.00	19.00 - 51.00	Normal
23.17	Leukocytes	4100	4000 - 13000			Normal
23.17	Platelets	208000	150000 - 400000			Normal
23.17	Basophils			0.00	0.00 - 2.00	Normal
23.26	Lymphocytes			16.00	19.00 - 51.00	Low
23.26	Leukocytes	4200	4000 - 13000			Normal
23.26	Platelets	185000	150000 - 400000			Normal
23.26	Basophils			0.00	0.00 - 2.00	Normal
23.36	Platelets	197000	150000 - 400000			Normal
23.36	Basophils			2.00	0.00 - 2.00	Normal
23.36	Lymphocytes			13.00	19.00 - 51.00	Low
23.36	Leukocytes	5200	4000 - 13000			Normal
23.43	Lymphocytes			14.00	19.00 - 51.00	Low
23.43	Leukocytes	5800	4000 - 13000			Normal
23.43	Platelets	206000	150000 - 400000			Normal
23.43	Basophils			2.00	0.00 - 2.00	Normal
23.52	Platelets	192000	150000 - 400000			Normal
23.52	Basophils			0.00	0.00 - 2.00	Normal
23.52	Lymphocytes			18.00	19.00 - 51.00	Low
23.52	Leukocytes	4700	4000 - 13000			Normal
23.60	Lymphocytes			16.00	19.00 - 51.00	Low
23.60	Leukocytes	5500	4000 - 13000			Normal
23.60	Platelets	201000	150000 - 400000			Normal
23.60	Basophils			0.00	0.00 - 2.00	Normal
23.67	Basophils			1.00	0.00 - 2.00	Normal
23.67	Lymphocytes			12.00	19.00 - 51.00	Low
23.67	Leukocytes	6700	4000 - 13000			Normal
23.67	Platelets	210000	150000 - 400000			Normal
23.75	Lymphocytes			11.00	19.00 - 51.00	Low
23.75	Leukocytes	4600	4000 - 13000			Normal
23.75	Platelets	194000	150000 - 400000			Normal
23.75	Basophils			1.00	0.00 - 2.00	Normal
23.83	Lymphocytes			7.00	19.00 - 51.00	Low
23.83	Leukocytes	6600	4000 - 13000			Normal
23.83	Platelets	218000	150000 - 400000			Normal
23.83	Basophils			0.00	0.00 - 2.00	Normal
23.90	Platelets	199000	150000 - 400000			Normal
23.90	Basophils			1.00	0.00 - 2.00	Normal
23.90	Lymphocytes			18.00	19.00 - 51.00	Low
23.90	Leukocytes	4400	4000 - 13000			Normal
23.98	Lymphocytes			15.00	19.00 - 51.00	Low
23.98	Leukocytes	4100	4000 - 13000			Normal
23.98	Platelets	191000	150000 - 400000			Normal
23.98	Basophils			0.00	0.00 - 2.00	Normal
24.06	Platelets	197000	150000 - 400000			Normal
24.06	Basophils			1.00	0.00 - 2.00	Normal
24.06	Lymphocytes			18.00	19.00 - 51.00	Low
24.06	Leukocytes	6100	4000 - 13000			Normal
24.08	Lymphocytes			12.00	19.00 - 51.00	Low
24.08	Leukocytes	10800	4000 - 13000			Normal
24.08	Platelets	185000	150000 - 400000			Normal
24.08	Basophils			0.00	0.00 - 2.00	Normal
24.18	Platelets	198000	150000 - 400000			Normal
24.18	Basophils			2.00	0.00 - 2.00	Normal
24.18	Lymphocytes			9.00	19.00 - 51.00	Low
24.18	Leukocytes	5000	4000 - 13000			Normal
24.26	Lymphocytes			12.00	19.00 - 51.00	Low
24.26	Leukocytes	5100	4000 - 13000			Normal
24.26	Platelets	190000	150000 - 400000			Normal
24.26	Basophils			0.00	0.00 - 2.00	Normal
24.37	Basophils			0.00	0.00 - 2.00	Normal
24.37	Lymphocytes			16.00	19.00 - 51.00	Low
24.37	Leukocytes	5000	4000 - 13000			Normal
24.37	Platelets	195000	150000 - 400000			Normal
24.45	Lymphocytes			16.00	19.00 - 51.00	Low
24.45	Leukocytes	4700	4000 - 13000			Normal
24.45	Platelets	193000	150000 - 400000			Normal
24.45	Basophils			2.00	0.00 - 2.00	Normal
24.54	Lymphocytes			9.00	19.00 - 51.00	Low
24.54	Leukocytes	5900	4000 - 13000			Normal
24.54	Platelets	187000	150000 - 400000			Normal
24.54	Basophils			0.00	0.00 - 2.00	Normal
24.62	Platelets	182000	150000 - 400000			Normal
24.62	Basophils			1.00	0.00 - 2.00	Normal
24.62	Lymphocytes			13.00	19.00 - 51.00	Low
24.62	Leukocytes	3700	4000 - 13000			Low
24.70	Lymphocytes			17.00	19.00 - 51.00	Low
24.70	Leukocytes	4200	4000 - 13000			Normal
24.70	Platelets	167000	150000 - 400000			Normal
24.70	Basophils			0.00	0.00 - 2.00	Normal
24.79	Platelets	184000	150000 - 400000			Normal
24.79	Basophils			0.00	0.00 - 2.00	Normal
24.79	Lymphocytes			14.00	19.00 - 51.00	Low
24.79	Leukocytes	5400	4000 - 13000			Normal
24.87	Leukocytes	5900	4000 - 13000			Normal
24.87	Platelets	199000	150000 - 400000			Normal
24.95	Leukocytes	5400	4000 - 13000			Normal
24.95	Platelets	188000	150000 - 400000			Normal
25.02	Leukocytes	4500	4000 - 13000			Normal
25.02	Lymphocytes			34.00	19.00 - 51.00	Normal
25.02	Platelets	187000	150000 - 400000			Normal
25.02	Basophils			0.00	0.00 - 2.00	Normal
25.10	Leukocytes	4100	4000 - 13000			Normal
25.10	Platelets	209000	150000 - 400000			Normal
25.20	Basophils			1.00	0.00 - 2.00	Normal
25.20	Platelets	199000	150000 - 400000			Normal
25.20	Lymphocytes			15.00	19.00 - 51.00	Low
25.20	Leukocytes	6600	4000 - 13000			Normal
25.29	Lymphocytes			28.00	19.00 - 51.00	Normal
25.29	Leukocytes	7100	4000 - 13000			Normal
25.29	Basophils			1.00	0.00 - 2.00	Normal
25.29	Platelets	221000	150000 - 400000			Normal
25.37	Platelets	187000	150000 - 400000			Normal
25.37	Lymphocytes			15.00	19.00 - 51.00	Low
25.37	Leukocytes	5600	4000 - 13000			Normal
25.37	Basophils			0.00	0.00 - 2.00	Normal
25.45	Leukocytes	5200	4000 - 13000			Normal
25.45	Basophils			1.00	0.00 - 2.00	Normal
25.45	Platelets	205000	150000 - 400000			Normal
25.45	Lymphocytes			8.00	19.00 - 51.00	Low
25.52	Platelets	223000	100000 - 500000			Normal
25.52	Lymphocytes			9.00	19.00 - 51.00	Low
25.52	Basophils			0.00	0.00 - 2.00	Normal
25.61	Basophils			0.00	0.00 - 2.00	Normal

* Measured under treatment or HSCT.

Plasma proteins

Age	Molecule[ℹ]	Value	Ref.range	Result
17.68	IgA	7	40 - 238 mg/dL	Low
17.68	IgM	45	48 - 228 mg/dL	Low
17.68	IgG	515	672 - 1536 mg/dL	Low
17.84	IgG	611	672 - 1536 mg/dL	Low
17.84	IgA	7	40 - 238 mg/dL	Low
17.84	IgM	57	48 - 228 mg/dL	Normal
18.09	IgM	66	48 - 228 mg/dL	Normal
18.09	IgG	681	672 - 1536 mg/dL	Normal
18.09	IgA	7	40 - 238 mg/dL	Low
18.17	IgM	73	48 - 228 mg/dL	Normal
18.17	IgG	760	672 - 1536 mg/dL	Normal
18.17	IgA	7	40 - 238 mg/dL	Low
18.28	IgA	7	40 - 238 mg/dL	Low
18.28	IgM	57	48 - 228 mg/dL	Normal
18.28	IgG	670	672 - 1536 mg/dL	Low
18.38	IgA	7	40 - 238 mg/dL	Low
18.38	IgM	57	48 - 228 mg/dL	Normal
18.38	IgG	635	672 - 1536 mg/dL	Low
18.54	IgG	799	672 - 1536 mg/dL	Normal
18.54	IgA	7	40 - 238 mg/dL	Low
18.54	IgM	62	48 - 228 mg/dL	Normal
18.62	IgM	74	48 - 228 mg/dL	Normal
18.62	IgG	882	672 - 1536 mg/dL	Normal
18.62	IgA	7	40 - 238 mg/dL	Low
18.70	IgM	81	48 - 228 mg/dL	Normal
18.70	IgG	851	672 - 1536 mg/dL	Normal
18.70	IgA	7	40 - 238 mg/dL	Low
18.77	IgM	95	48 - 228 mg/dL	Normal
18.77	IgG	925	672 - 1536 mg/dL	Normal
18.77	IgA	7	40 - 238 mg/dL	Low
18.86	IgA	7	40 - 238 mg/dL	Low
18.86	IgM	89	48 - 228 mg/dL	Normal
18.86	IgG	903	672 - 1536 mg/dL	Normal
18.95	IgG	820	672 - 1536 mg/dL	Normal
18.95	IgA	7	40 - 238 mg/dL	Low
18.95	IgM	90	48 - 228 mg/dL	Normal
19.13	IgM	94	48 - 228 mg/dL	Normal
19.13	IgG	999	672 - 1536 mg/dL	Normal
19.13	IgA	7	40 - 238 mg/dL	Low
19.47	IgM	78	48 - 228 mg/dL	Normal
19.47	IgG	950	672 - 1536 mg/dL	Normal
19.47	IgA	7	40 - 238 mg/dL	Low
19.63	IgM	77	48 - 228 mg/dL	Normal
19.63	IgG	932	672 - 1536 mg/dL	Normal
19.63	IgA	7	40 - 238 mg/dL	Low
19.70	IgA	7	40 - 238 mg/dL	Low
19.70	IgM	91	48 - 228 mg/dL	Normal
19.70	IgG	947	672 - 1536 mg/dL	Normal
19.71	IgG	1370	672 - 1536 mg/dL	Normal
19.75	IgG	694	672 - 1536 mg/dL	Normal
20.02	IgA	7	40 - 238 mg/dL	Low
20.02	IgG	774	672 - 1536 mg/dL	Normal
20.02	IgM	134	48 - 228 mg/dL	Normal
20.12	IgA	7	40 - 238 mg/dL	Low
20.12	IgG	616	672 - 1536 mg/dL	Low
20.12	IgM	74	48 - 228 mg/dL	Normal
20.63	IgM	65	48 - 228 mg/dL	Normal
20.63	IgA	7	40 - 238 mg/dL	Low
20.63	IgG	636	672 - 1536 mg/dL	Low
20.79	IgM	79	48 - 228 mg/dL	Normal
20.79	IgA	7	40 - 238 mg/dL	Low
20.79	IgG	812	672 - 1536 mg/dL	Normal
20.87	IgA	7	40 - 238 mg/dL	Low
20.87	IgG	796	672 - 1536 mg/dL	Normal
20.87	IgM	85	48 - 228 mg/dL	Normal
20.94	IgA	7	40 - 238 mg/dL	Low
20.94	IgG	853	672 - 1536 mg/dL	Normal
20.94	IgM	92	48 - 228 mg/dL	Normal
21.02	IgA	7	40 - 238 mg/dL	Low
21.02	IgG	732	672 - 1536 mg/dL	Normal
21.02	IgM	84	48 - 228 mg/dL	Normal
21.10	IgM	91	48 - 228 mg/dL	Normal
21.10	IgA	7	40 - 238 mg/dL	Low
21.10	IgG	838	672 - 1536 mg/dL	Normal
21.17	IgM	91	48 - 228 mg/dL	Normal
21.17	IgA	7	40 - 238 mg/dL	Low
21.17	IgG	859	672 - 1536 mg/dL	Normal
21.25	IgG	808	672 - 1536 mg/dL	Normal
21.25	IgM	81	48 - 228 mg/dL	Normal
21.25	IgA	7	40 - 238 mg/dL	Low
21.33	IgA	7	40 - 238 mg/dL	Low
21.33	IgG	796	672 - 1536 mg/dL	Normal
21.33	IgM	76	48 - 228 mg/dL	Normal
21.40	IgA	7	40 - 238 mg/dL	Low
21.40	IgG	810	672 - 1536 mg/dL	Normal
21.40	IgM	84	48 - 228 mg/dL	Normal
21.56	IgM	106	48 - 228 mg/dL	Normal
21.56	IgA	6	40 - 238 mg/dL	Low
21.56	IgG	914	672 - 1536 mg/dL	Normal
21.63	IgM	91	48 - 228 mg/dL	Normal
21.63	IgA	12	40 - 238 mg/dL	Low
21.63	IgG	859	672 - 1536 mg/dL	Normal
21.71	IgM	86	48 - 228 mg/dL	Normal
21.71	IgA	7	40 - 238 mg/dL	Low
21.71	IgG	818	672 - 1536 mg/dL	Normal
21.79	IgA	7	40 - 238 mg/dL	Low
21.79	IgG	903	672 - 1536 mg/dL	Normal
21.79	IgM	89	48 - 228 mg/dL	Normal
21.87	IgA	7	40 - 238 mg/dL	Low
21.87	IgG	700	672 - 1536 mg/dL	Normal
21.87	IgM	69	48 - 228 mg/dL	Normal
21.94	IgA	7	40 - 238 mg/dL	Low
21.94	IgG	739	672 - 1536 mg/dL	Normal
21.94	IgM	64	48 - 228 mg/dL	Normal
22.32	IgM	66	48 - 228 mg/dL	Normal
22.32	IgA	7	40 - 238 mg/dL	Low
22.32	IgG	713	672 - 1536 mg/dL	Normal
22.40	IgM	62	48 - 228 mg/dL	Normal
22.40	IgA	7	40 - 238 mg/dL	Low
22.40	IgG	744	672 - 1536 mg/dL	Normal
22.48	IgA	7	40 - 238 mg/dL	Low
22.48	IgG	683	672 - 1536 mg/dL	Normal
22.48	IgM	66	48 - 228 mg/dL	Normal
22.63	IgA	7	40 - 238 mg/dL	Low
22.63	IgG	739	672 - 1536 mg/dL	Normal
22.63	IgM	72	48 - 228 mg/dL	Normal
22.71	IgA	7	40 - 238 mg/dL	Low
22.71	IgG	778	672 - 1536 mg/dL	Normal
22.71	IgM	77	48 - 228 mg/dL	Normal
22.78	IgM	77	48 - 228 mg/dL	Normal
22.78	IgA	7	40 - 238 mg/dL	Low
22.78	IgG	720	672 - 1536 mg/dL	Normal
22.94	IgM	67	48 - 228 mg/dL	Normal
22.94	IgA	7	40 - 238 mg/dL	Low
22.94	IgG	649	672 - 1536 mg/dL	Low
23.01	IgG	697	672 - 1536 mg/dL	Normal
23.01	IgM	66	48 - 228 mg/dL	Normal
23.01	IgA	7	40 - 238 mg/dL	Low
23.09	IgA	7	40 - 238 mg/dL	Low
23.09	IgG	635	672 - 1536 mg/dL	Low
23.09	IgM	69	48 - 228 mg/dL	Normal
23.17	IgA	7	40 - 238 mg/dL	Low
23.17	IgG	687	672 - 1536 mg/dL	Normal
23.17	IgM	80	48 - 228 mg/dL	Normal
23.26	IgM	84	48 - 228 mg/dL	Normal
23.26	IgA	7	40 - 238 mg/dL	Low
23.26	IgG	686	672 - 1536 mg/dL	Normal
23.36	IgM	80	48 - 228 mg/dL	Normal
23.36	IgA	7	40 - 238 mg/dL	Low
23.36	IgG	641	672 - 1536 mg/dL	Low
23.43	IgM	75	48 - 228 mg/dL	Normal
23.43	IgA	7	40 - 238 mg/dL	Low
23.43	IgG	629	672 - 1536 mg/dL	Low
23.52	IgA	7	40 - 238 mg/dL	Low
23.52	IgG	624	672 - 1536 mg/dL	Low
23.60	IgA	7	40 - 238 mg/dL	Low
23.60	IgG	662	672 - 1536 mg/dL	Low
23.60	IgM	71	48 - 228 mg/dL	Normal
24.54	IgA	7	40 - 238 mg/dL	Low
24.54	IgG	656	672 - 1536 mg/dL	Low
24.54	IgM	73	48 - 228 mg/dL	Normal
24.79	IgA	7	40 - 238 mg/dL	Low
24.79	IgG	662	672 - 1536 mg/dL	Low
24.79	IgM	68	48 - 228 mg/dL	Normal
24.95	IgM	83	48 - 228 mg/dL	Normal
24.95	IgA	7	40 - 238 mg/dL	Low
24.95	IgG	620	672 - 1536 mg/dL	Low
25.02	IgA	7	40 - 238 mg/dL	Low
25.02	IgG	604	672 - 1536 mg/dL	Low
25.02	IgM	81	48 - 228 mg/dL	Normal
25.20	IgA	7	40 - 238 mg/dL	Low
25.20	IgG	615	672 - 1536 mg/dL	Low
25.20	IgM	80	48 - 228 mg/dL	Normal
25.29	IgA	7	40 - 238 mg/dL	Low
25.29	IgG	560	672 - 1536 mg/dL	Low
25.29	IgM	68	48 - 228 mg/dL	Normal
25.37	IgG	614	672 - 1536 mg/dL	Low
25.45	IgG	712	672 - 1536 mg/dL	Normal
25.52	IgG	693	672 - 1536 mg/dL	Normal
25.52	IgA	7	40 - 238 mg/dL	Low
25.52	IgM	86	48 - 228 mg/dL	Normal
25.61	IgG	615	672 - 1536 mg/dL	Low
25.70	IgM	109	48 - 228 mg/dL	Normal
25.70	IgG	655	672 - 1536 mg/dL	Low
25.70	IgA	7	40 - 238 mg/dL	Low
25.77	IgG	652	672 - 1536 mg/dL	Low
25.83	IgM	207	40 - 230 mg/dL	Normal
25.83	IgG	652	700 - 1600 mg/dL	Low
25.83	IgA	6	70 - 400 mg/dL	Low
25.85	IgA	6	70 - 400 mg/dL	Low
25.85	IgG	652	700 - 1600 mg/dL	Low
25.85	IgE	18	10 - 100 IU/ml	Normal
25.85	IgM	207	40 - 230 mg/dL	Normal
25.85	IgG	648	672 - 1536 mg/dL	Low
25.93	IgG	585	672 - 1536 mg/dL	Low
26.02	IgA	7	40 - 238 mg/dL	Low
26.02	IgG	597	672 - 1536 mg/dL	Low
26.02	IgM	122	48 - 228 mg/dL	Normal
26.10	IgG	564	672 - 1536 mg/dL	Low
26.21	IgG	532	672 - 1536 mg/dL	Low
26.29	IgG	656	672 - 1536 mg/dL	Low
26.37	IgG	649	672 - 1536 mg/dL	Low
26.44	IgG	643	672 - 1536 mg/dL	Low
26.52	IgG	683	672 - 1536 mg/dL	Normal
26.61	IgG	677	672 - 1536 mg/dL	Normal
26.69	IgG	699	672 - 1536 mg/dL	Normal
26.77	IgG	674	672 - 1536 mg/dL	Normal
26.84	IgG	674	672 - 1536 mg/dL	Normal
26.92	IgG	642	672 - 1536 mg/dL	Low
27.00	IgG	721	672 - 1536 mg/dL	Normal

[ℹ] shows name on hover
* Measured during IVIG or other treatment.

Phenotypic & functional assays

Age	Parameter[ℹ]	Result*	Cells	Methods[ℹ]	Stimuli	Ref.

[ℹ] shows more on hover
* Compared to WT controls
📊 shows raw values on hover